24-11114S (2024-2026) Molecular glues as a tool for targeted degradation of cyclin K V. Kryštof (co-investigator)
23-06931S (2023-2025) Phenylsufates in plants and foods: Occurrence, environmental factors and health risk J. Grúz (principal investigator)
23-05389S (2023-2025) Novel CB2 and BChE modulators against Parkinson's disease and related pathologies M. Kvasnica (principal investigator), G. Gonzalez (team member)
23-05462S (2023-2025) Targeting of FLT3 using new dual inhibitors as a therapeutic approach in MLL-rearranged acute myeloid leukemia V. Kryštof (principal investigator)
21-39625L (2021-2023) NECESSITY – New chemical entities for modulating SARS-CoV2 activity V. Kryštof (principal investigator)
21-06553S (2021-2024) Targeting oncogenic kinases with small molecules V. Kryštof (principal investigator)
21-07661S (2021-2023) Modulation of plant abiotic stress responses by regulation of cytokinin and purineinterconversion enzymes D. Kopečný (principal investigator)
Palacký University
IGA_PrF_2023_012 (2023) Small molecule inhibitors of oncogenic kinase FLT3 V. Kryštof (principal investigator)
IGA_PrF_2022_007 (2022) Molecular effects of enzyme inhibitors V. Kryštof (principal investigator)
UPOL DSGC-2021-0158 (2022) Protein production for experimental and structural biology M. Peřina (principal investigator)
UPOL JG_2020_001 (2020-2022) Functional characterization of aldehyde dehydrogenases putatively associated with the evolutionary transition from water to land M. Kopečná (principal investigator)
IGA_PrF_2021_007 (2021-2022) Molecular effects of enzyme inhibitors V. Kryštof (principal investigator)
Ministry of Education, Youth and Sports
OP VVV ENOCH CZ.02.1.01/0.0/0.0/16_019/0000868 (9/2018 – 6/2023), financed from OPRDE Molecular, cellular and clinical approach to healthy ageing V. Kryštof (investigator)
Past Projects
20-26232S (2020-2022) Cold-light interaction in Arabidopsis cold acclimation – ontogenic and phyllotactic perspective J. Grúz (co-investigator)
19-09086S (2019-2021) Dual FLT3/CDK9 inhibition as a possible therapeutical approach for mixed lineage leukemia V. Kryštof (principal investigator)
19-08410S (2019-2021) Substituted imidazopyrimidines: Structure-based design and development of specific inhibitors V. Kryštof (co-investigator)
GAČR 18-03847S (2018-2020) Pseudopeptide proteasome inhibitors V. Kryštof (principal investigator)
GAČR 18-07563S (2018-2020) Functional and stuctural study on plant enzymes involved in cytokinin degradation and aldehyde detoxification D. Kopečný (co-investigator)
AZV 17-31834A (2017-2020) Targeting BCR signalosome in B-cell malignancies V. Kryštof (principal investigator)
PRF UP, IGA_PrF_2017_014 (2017-2018) Molecular mechanisms of effects of protein kinase inhibitors V. Kryštof (principal investigator)
PRF UP, IGA_PrF_2017_016 (2017-2018) Studium enzymů aldehyddehydrogenasy a S-nitrosoglutathionreduktasy, cytokininových receptorů, strigolaktonů, ergoidních alkaloidů a reaktivních forem kyslíku a dusíku a jejich vliv na stresové odpovědi rostlin M. Kopečná (principal investigator)
MŠMT 7AMB17DE009 (2017-2018) Study on enzymes involved in the metabolism of purines, pyrimidines and cytokinins in plants D. Kopečný (principal investigator)
AZV 15-28951A (2015-2018) New kinase inhibitors to treat acute myeloid leukemia V. Kryštof (principal investigator)
GAČR 15-15264S (2015-2017) Targeted Transport of Purine Cyclin-dependent Kinase Inhibitors into Cancer Cells V. Kryštof (principal investigator)
GAČR 15-17282Y (2015-2017) Chemical genetic analysis of role of cyclin-dependent kinases in cancer cell lines R. Jorda (principal investigatorl)
GAČR 15-22322S (2015-2017) Molecular modulation of cytokinin metabolism in model plants Physcomitrella and maize focused on function of nucleosidases D. Kopečný (co-investigator)
GAČR 14-27669P (2014-2018) The study of molecular mechanisms of anticancer and antiangiogenic activities of brassinosteroids L. Rárová (principal investigator)
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