2024

  • Vrzalova A., Vrzal R., Nádvorník P., Šebela M., Dvořák Z. (2024) Modulation of aryl hydrocarbon receptor activity by halogenated indoles. Bioorganic & Medicinal Chemistry 114, 117964  [IF2023 3.3] https://doi.org/10.1016/j.bmc.2024.117964 Vančo, J., Trávníček, Z., Malina, T., Hošek, J., Dvořák, Z., (2024) Cellular Effects of Cationic Copper(II) Schiff Base Complexes: Anti‐Inflammatory and Antiproliferative Properties. ChemMedChem. [IF2023 3.6] https://doi.org/10.1002/cmdc.202400214

  • Kobrlová, L., Čížková, J., Zoulová, V., Vejvodová, K., Hřibová, E., (2024) First insight into the genomes of the Pulmonaria officinalis group (Boraginaceae) provided by repeatome analysis and comparative karyotyping. BMC Plant Biology 24 [IF2023 4.3] https://doi.org/10.1186/s12870-024-05497-4

  • Karafiátová, M., Bojdová, T., Stejskalová, M., Harnádková, N., Kumar, V., Houben, A., Chen, J., Doležalová, A., Honys, D., Bartoš, J., (2024). Unravelling the unusual: chromosome elimination, nondisjunction and extra pollen mitosis characterize the B chromosome in wild sorghum. New Phytologist 243, 1840–1854 [IF2023 8.3] https://doi.org/10.1111/nph.19954

  • Massoud SS, Mautner FA, Louka FR, Salem NMH, Fischer RC, Torvisco A, Vančo J, Belza J, Dvořák Z, Trávníček Z. (2024) Structurally diverse zinc(II) complexes containing tripodal tetradentate phenoxido-amines with promising antiproliferative effects. Dalton Trans. 2024 Jul 23;53(29):12261-12280 [IF2023 3.5] doi: 10.1039/d4dt00942h

  • Travnicek, Z., Vanco, J., Belza, J., Zoppellaro, G., Dvorak, Z., Belakova, B., Schmid, J. A., Molcanova, L. & Smejkal, K. (2024). C-Geranylated flavanone diplacone enhances in vitro antiproliferative and anti-inflammatory effects in its copper(II) complexes. J Inorg Biochem 258: 112639 [IF2023 3.8]  https://doi.org/10.1016/j.jinorgbio.2024.112639

  • Durdakova, M., Kolackova, M., Ridoskova, A., Cernei, N., Pavelicova, K., Urbis, P., Richtera, L., Pelcova, P., Adam, V. & Huska, D. (2024). Exploring the potential nutritional benefits of Arthrospira maxima and Chlorella vulgaris: A focus on vitamin B(12), amino acids, and micronutrients. Food Chem 452: 139434. [IF2022 8.8] https://doi.org/10.1016/j.foodchem.2024.139434

  • Belza, J., Trávníček, Z., Vančo, J., Čajan, M., Hošek, J. & Dvořák, Z. (2024). Gold(I) N-Heterocyclic Carbene Complexes with 7-Azaindoles Demonstrates In Vitro Antiproliferative Effects on Ovarian Cancer Cells and Anti-inflammatory Activity. Organometallics 43(10): 1155-1164 [IF2022 3.84]  DOI: 10.1021/acs.organomet.4c00093

  • Šafářová, D., Candresse, T., Veselská, J. & Navrátil, M. (2024). Novel Betanucleorhabdoviruses Infecting Elderberry (Sambucus nigra L.): Genome Characterization and Genetic Variability. Pathogens 13(6): 445.[IF2022 3.7]  https://doi.org/10.3390/pathogens13060445

  • Fiaschi, M., Vančo, J., Biancalana, L., Malina, T., Dvořák, Z., Funaioli, T., Zacchini, S., Guelfi, M., Trávníček, Z. & Marchetti, F. (2024). Synthesis and studies of aqueous-stable diruthenium aminocarbyne complexes uncovered an <i>N</i>-indolyl derivative as a prospective anticancer agent. Inorganic Chemistry Frontiers.[IF2022 7.0] https://doi.org/10.1039/D4QI00096J

  • Trávníček, Z., Vančo, J., Čajan, M., Belza, J., Popa, I., Hošek, J., Lenobel, R. & Dvořák, Z. (2024). Gold(I) N‐heterocyclic carbene (NHC) complexes containing 6‐mercaptopurine derivatives and their in vitro anticancer and anti‐inflammatory effects. Applied Organometallic Chemistry 38(4). [IF2022 3.9] https://doi.org/10.1002/aoc.7401

  • Vladejić J, Kovacik M, Zwyrtková J, Szurman-Zubrzycka M, Doležel J, Pecinka A. (2024) Zeocin-induced DNA damage response in barley and its dependence on ATR. Sci Rep. Feb 7;14(1):3119. [IF2022 4.6] doi: 10.1038/s41598-024-53264-0.

  • Kiss, T., Šafářová, D., Navrátil, M.,Nečas, T. (2024). Molecular Characterization of ‘Candidatus Phytoplasma prunorum’ in the Czech Republic and Susceptibility of Apricot Rootstocks to the Two Most Abundant Haplotypes. Microorganisms 12(2): 399.[IF2022 4.5] https://doi.org/10.3390/microorganisms12020399

  • Dvořák Z., Vyhlídalová B., Pečinková P., Li H, Anzenbacher P, Špičáková A, Anzenbacherová E, Chow V, Liu J, Krause H, Wilson D, Berés T, Tarkowski P, Chen D, Mani S (2024) In vitro safety signals for potential clinical development of the anti-inflammatory pregnane X receptor agonist FKK6. Bioorg Chem. Jan 19;144:107137 [IF2022 5.1] doi: 10.1016/j.bioorg.2024.107137.

  • Pavlovič, A., Kopečná, M., Hloušková, L., Koller, J., Hřivňacký, M., Ilík, P., Bartoš, J., (2024) Diethyl ether anaesthesia inhibits de‐etiolation of barley seedlings by locking them in intermediate skoto‐photomorphogenetic state. Physiologia Plantarum 176. [IF2022 6.4] https://doi.org/10.1111/ppl.14144

  • Trávníček Z, Vančo J, Belza J, Zoppellaro G, Dvořák Z. (2024) Dinuclear copper(II) complexes with a bridging bis(chalcone) ligand reveal considerable in vitro cytotoxicity on human cancer cells and enhanced selectivity. J Inorg Biochem. Jan 4;252:112481. [IF2022 3.9] doi: 10.1016/j.jinorgbio.2024.112481

  • Kaduchová, K., Čmiel, V., Koláčková, V., Pecinka, A., (2024). EasyClick: an improved system for confocal microscopy of live roots with a user-optimized sample holder. Planta 259. [IF2022 4.3] https://doi.org/10.1007/s00425-023-04293-y

  • Pavlu S, Nikumbh S, Kovacik M, An T, Lenhard B, Simkova H, Navratilova P. (2024) Core promoterome of barley embryo. Comput Struct Biotechnol J. Dec 5;23:264-277. [IF2022 6.0] doi: 10.1016/j.csbj.2023.12.003.

2023

  • Vrzal, R., Marcalíková, A., Krasulová, K., Zemánková, L. & Dvořák, Z. (2023). Jasmone Is a Ligand-Selective Allosteric Antagonist of Aryl Hydrocarbon Receptor (AhR). International Journal of Molecular Sciences 24(21): 15655. [IF2022 5.6] https://doi.org/10.3390/ijms242115655

  • Sladekova, L., Zgarbova, E., Vrzal, R., Vanda, D., Soural, M., Jakubcova, K., Vazquez-Gomez, G., Vondracek, J. & Dvorak, Z. (2023). Switching on/off aryl hydrocarbon receptor and pregnane X receptor activities by chemically modified tryptamines. Toxicol Lett. [IF2022 3.5] https://doi.org/10.1016/j.toxlet.2023.09.012

  • Bresciani, G., Vanco, J., Funaioli, T., Zacchini, S., Malina, T., Pampaloni, G., Dvorak, Z., Travnicek, Z. & Marchetti, F. (2023). Anticancer Potential of Diruthenium Complexes with Bridging Hydrocarbyl Ligands from Bioactive Alkynols. Inorg Chem. 62: 15875-15890 [IF2022 4.6] doi: 10.1021/acs.inorgchem.3c01731

  • Vázquez-Gómez G., Petráš J., Dvořák Z., Vondráček J.(2023) Aryl hydrocarbon receptor (AhR) and pregnane X receptor (PXR) play both distinct and common roles in the regulation of colon homeostasis and intestinal carcinogenesis. Biochemical Pharmacology 216:115797 [IF2022 5.8] https://doi.org/10.1016/j.bcp.2023.115797

  • Šafářová D, Zrníková E, Holušová K, Ouředníčková J, Starý M, Navrátil M. Molecular Characterization of Mitogenome of Cacopsylla picta and Cacopsylla melanoneura, Two Vector Species of ‘Candidatus Phytoplasma mali’. Agronomy. 2023; 13(9):2210. [IF2022 2.1] https://doi.org/10.3390/agronomy13092210

  • Kaduchová, K., Marchetti, C., Ovečka, M., Galuszka, P., Bergougnoux, V., Šamaj, J. & Pecinka, A. (2023). Spatial organization and dynamics of chromosomes and microtubules during barley mitosis. The Plant Journal 115(3): 602-613. [IF2022 7.091] doi.org/10.1111/tpj.16392.

  • Rollin, J., Bester, R., Brostaux, Y., Caglayan, K., De Jonghe, K., Eichmeier, A., Foucart, Y., Haegeman, A., Koloniuk, I., Kominek, P., Maree, H., Onder, S., Posada Céspedes, S., Roumi, V., Šafářová, D., Schumpp, O., Ulubas Serce, C., Sõmera, M., Tamisier, L., Vainio, E., Van Der Vlugt, R. A. & Massart, S. (2023). Detection of single nucleotide polymorphisms in virus genomes assembled from high-throughput sequencing data: large-scale performance testing of sequence analysis strategies. PeerJ 11: e15816. [IF2022 2.7] doi 10.7717/peerj.15816

  • Fakhimahmadi, A., Hasanaj, I., Hofstetter, G., Pogner, C., Gorfer, M., Wiederstein, M., Szepannek, N., Bianchini, R., Dvorak, Z., Jensen, S.A., et al. (2023) Nutritional Provision of Iron Complexes by the Major Allergen Alt a 1 to Human Immune Cells Decreases Its Presentation. Int. J. Mol. Sci. 24, 11934. [IF2022 5.6] doi.org/10.3390/ijms241511934 

  • Sladekova, L., Mani, S. & Dvorak, Z. (2023). Ligands and agonists of the aryl hydrocarbon receptor AhR: Facts and Myths. Biochem Pharmacol: 115626 [IF2022 5.8] https://doi.org/10.1016/j.bcp.2023.115626

  • Ondrová, K., Zůvalová, I., Vyhlídalová, B., Krasulová, K., Miková, E., Vrzal, R., Nádvorník, P., Nepal, B., Kortagere, S., Kopečná, M., Kopečný, D., Šebela, M., Rastinejad, F., Pu, H., Soural, M., Rolfes, K. M., Haarmann-Stemmann, T., Li, H., Mani, S. & Dvořák, Z. (2023). Monoterpenoid aryl hydrocarbon receptor allosteric antagonists protect against ultraviolet skin damage in female mice. Nature Communications 14(1) [IF2022 16.6] https://doi.org/10.1038/s41467-023-38478-6

  • Majka, M., Janakova, E., Jakobson, I., Jarve, K., Capal, P., Korchanova, Z., Lampar, A., Juracka, J. & Valarik, M. (2023). The chromatin determinants and Ph1 gene effect at wheat sites with contrasting recombination frequency. J Adv Res.[IF2022 10.7] https://doi.org/10.1016/j.jare.2023.01.002

  • Svacina, R., Hlouskova, L., Karafiatova, M. & Bartos, J. (2023). Scoring the number of B chromosomes in Zea mays L. using droplet digital PCR assay. Plant Methods 19(1): 43.[IF2022 5.1] DOI: 10.1186/s13007-023-01019-9

  • Strejckova, B., Mazzucotelli, E., Cegan, R., Milec, Z., Brus, J., Cakir, E., Mastrangelo, A. M., Ozkan, H. & Safar, J. (2022). Wild emmer wheat, the progenitor of modern bread wheat, exhibits great diversity in the VERNALIZATION1 gene. Front Plant Sci 13: 1106164 [IF2022 5.6] https://doi.org/10.3389/fpls.2022.1106164

  • Korchanova, Z., Svec, M., Janakova, E., Lampar, A., Majka, M., Holusova, K., Bonchev, G., Juracka, J., Capal, P. & Valarik, M. (2022). Identification, High-Density Mapping, and Characterization of New Major Powdery Mildew Resistance Loci From the Emmer Wheat Landrace GZ1. Front Plant Sci 13: 897697 [IF2022 5.6] https://doi.org/10.3389/fpls.2022.897697

  • Kitner, M., Thines, M., Sedlářová, M., Vaculná, L., Bán, R., Körösi, K., Iwebor, M., Antonova, T., Ali, T., Nádvorník, P., Lebeda, A. & Spring, O. (2023). Genetic structure of  Plasmopara halstedii populations across Europe and South Russia. Plant Pathology 72(2): 361-375. [IF2022 2.7] https://doi.org/10.1111/ppa.13666

  • Dvorak Tomastikova, E., Yang, F., Mlynarova, K., Hafidh, S., Schorova, S., Kusova, A., Pernisova, M., Prerovska, T., Klodova, B., Honys, D., Fajkus, J., Pecinka, A. & Prochazkova Schrumpfova, P. (2023). RUVBL proteins are involved in plant gametophyte development. Plant J. 114(2):325-337 [IF2022 7.2] doi: 10.1111/tpj.16136

  • Dvorak Tomastikova, E., Prochazkova, K., Yang, F., Jemelkova, J., Finke, A., Dorn, A., Said, M., Puchta, H. & Pecinka, A. (2023). SMC5/6 complex-mediated SUMOylation stimulates DNA-protein crosslink repair in Arabidopsis. Plant Cell 35(5):1532-1547 [IF2022 11.6] doi: 10.1093/plcell/koad020

  • Dvorak, Z., Li, H. & Mani, S. (2023) Microbial Metabolites as Ligands to Xenobiotic Receptors: Chemical Mimicry as Potential Drugs of the Future. Drug Metabolism and Disposition 51(2):219-227. [IF2022 3.9] DOI: 10.1124/dmd.122.000860

  • Trávníček, Z., Vančo, J., Belza, J., Hošek, J., Dvořák, Z., Lenobel, R., Popa, I., Šmejkal, K., Uhrin, P. (2023) The Gold(I) Complex with Plant Hormone Kinetin Shows Promising In Vitro Anticancer and
    PPARγ Properties. Int. J. Mol. Sci. 24, 2293. [IF2022 5.6] https://doi.org/10.3390/ijms24032293

  • Zgarbová, E., Vrzal, R. (2023) The Impact of Indoles Activating the Aryl Hydrocarbon Receptor on Androgen Receptor Activity in the 22Rv1 Prostate Cancer Cell Line. Int. J. Mol. Sci. 24, 502. [IF2022 5.6] https://doi.org/10.3390/ijms24010502

  • Zgarbová, E., Vrzal R. (2023) Skatole: A thin red line between its benefits and toxicity. Biochimie 208: 1-12 [IF2022 3.9] https://doi.org/10.1016/j.biochi.2022.12.014

  • Trávníček, Z.; Malina, T.; Vančo, J.; Šebela, M.; Dvořák, Z. (2023) Heteroleptic Copper(II) Complexes Containing 2′-Hydroxy-4- (Dimethylamino)Chalcone Show Strong Antiproliferative Activity. Pharmaceutics, 15, 307. [IF2022 5.4] https://doi.org/10.3390/pharmaceutics15020307

  • Massoud, S. S., Louka, F. R., Salem, N. M. H., Fischer, R. C., Torvisco, A., Mautner, F. A., Vanco, J., Belza, J., Dvorak, Z. & Travnicek, Z. (2023). Dinuclear doubly bridged phenoxido copper(II) complexes as efficient anticancer agents. Eur J Med Chem 246: 114992 [IF2022 6.7] https://doi.org/10.1016/j.ejmech.2022.114992

2022

  • Zuo, S., Yadala, R., Yang, F., Talbert, P., Fuchs, J., Schubert, V., Ahmadli, U., Rutten, T., Pecinka, A., Lysak, M. A. & Lermontova, I. (2022). Recurrent Plant-Specific Duplications of KNL2 and Its Conserved Function as a Kinetochore Assembly Factor. Mol Biol Evol 39(6). [IF 10.7] https://doi.org/10.1093/molbev/msac123

  • Vladejic, J., Yang, F., Dvorak Tomastikova, E., Dolezel, J., Palecek, J. J. & Pecinka, A. (2022). Analysis of BRCT5 domain-containing proteins reveals a new component of DNA damage repair in Arabidopsis. Front Plant Sci 13: 1023358 [IF 5.6] https://doi.org/10.3389/fpls.2022.1023358

  • Regner, A.; Szepannek, N.; Wiederstein, M.; Fakhimahmadi, A.; Paciosis, L.F.; Blokhuis, B.R.; Redegeld, F.A.; Hofstetter, G.; Dvorak, Z.; Jensen-Jarolim, E.; et al. (2022) Binding to Iron Quercetin Complexes Increases the Antioxidant Capacity of the Major Birch Pollen Allergen Bet v 1 and Reduces Its Allergenicity. Antioxidants, 12, 42. [IF 7.0] https:// doi.org/10.3390/antiox12010042

  • Michaudel, C., Danne, C., Agus, A., Magniez, A., Aucouturier, A., Spatz, M., Lefevre, A., Kirchgesner, J., Rolhion, N., Wang, Y., Lavelle, A., Galbert, C., Da Costa, G., Poirier, M., Lapiere, A., Planchais, J., Nadvornik, P., Illes, P., Oeuvray, C., Creusot, L., Michel, M. L., Benech, N., Bourrier, A., Nion-Larmurier, I., Landman, C., Richard, M. L., Emond, P., Seksik, P., Beaugerie, L., Arguello, R. R., Moulin, D., Mani, S., Dvorak, Z., Bermudez-Humaran, L. G., Langella, P. & Sokol, H. (2022). Rewiring the altered tryptophan metabolism as a novel therapeutic strategy in inflammatory bowel diseases. Gut  327337 [IF 24.5]  http://dx.doi.org/10.1136/gutjnl-2022-327337

  • Vrzalová A., Pečinková P., Illés P., Gurská S., Džubák P., Szotkowski M., Hajdúch M., Mani S. and Dvořák Z. (2022) Mixture Effects of Tryptophan Intestinal Microbial Metabolites on Aryl Hydrocarbon Receptor Activity. Int. J. Mol. Sci. 23, 10825. [IF 5.6] https://doi.org/10.3390/ijms231810825

  • Karasova, M., Prochazkova, J., Tylichova, Z., Fedr, R., Ciganek, M., Machala, M., Dvorak, Z., Vyhlidalova, B., Zuvalova, I., Ehrmann, J., Bouchal, J., Andrysik, Z. & Vondracek, J. (2022). Inhibition of Aryl Hydrocarbon Receptor (AhR) Expression Disrupts Cell Proliferation and Alters Energy Metabolism and Fatty Acid Synthesis in Colon Cancer Cells. Cancers 14(17). [IF 5.2] https://doi.org/10.3390/cancers14174245

  • Modoux, M., Rolhion, N., Lefevre, J. H., Oeuvray, C., Nadvornik, P., Illes, P., Emond, P., Parc, Y., Mani, S., Dvorak, Z. & Sokol, H. (2022). Butyrate acts through HDAC inhibition to enhance aryl hydrocarbon receptor activation by gut microbiota-derived ligands. Gut Microbes 14(1): 2105637. [IF 12.2]  https://doi.org/10.1080/19490976.2022.2105637

  • Imran, S. J., Vagaska B., Kriska J., Anderova M., Bortolozzi M., Gerosa G., Ferretti P. and Vrzal R. (2022) Aryl Hydrocarbon Receptor (AhR)-Mediated Signaling iniPSC-Derived Human Motor Neurons. Pharmaceuticals 15, 828. [IF 4.6] https://doi.org/10.3390/ph15070828

  • Iacopini, D., Vančo, J., Di Pietro, S., Bordoni, V., Zacchini, S., Marchetti, F., Dvořák, Z., Malina, T., Biancalana, L., Trávníček, Z. & Di Bussolo, V. (2022). New glycoconjugation strategies for Ruthenium(II) arene complexes via phosphane ligands and assessment of their antiproliferative activity. Bioorg Chem 126: 105901. [IF 5.1] doi.org/10.1016/j.bioorg.2022.105901

  • Grycová, A., Joo, H., Maier, V., Illés, P., Vyhlídalová, B., Poulíková, K., Sládeková, L., Nádvorník, P., Vrzal, R., Zemánková, L., Pečinková, P., Poruba, M., Zapletalová, I., Večeřa, R., Anzenbacher, P., Ehrmann, J., Ondra, P., Jung, J.-W., Mani, S. & Dvořák, Z. (2022). Targeting the Aryl Hydrocarbon Receptor with Microbial Metabolite Mimics Alleviates Experimental Colitis in Mice. Journal of Medicinal Chemistry 65(9): 6859-6868.[IF 7.3] doi.org/10.1021/acs.jmedchem.2c00208

  • Pavek, P., Dusek, J., Smutny, T., Lochman, L., Kucera, R., Skoda, J., Smutna, L., Kamaraj, R., Soucek, P., Vrzal, R. & Dvorak, Z. (2022). Gene Expression Profiling of 1α,25(OH) Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic‐Metabolizing Genes. Molecular Nutrition & Food Research 66(9): 2200070 [IF 5.2] doi.org/10.1002/mnfr.202200070

  • Yang, F., Pečinka P. (2022) Multiple Roles of SMC5/6 Complex during Plant Sexual Reproduction. International Journal of Molecular Sciences 23: 4503 [IF 5.6] doi.org/10.3390/ijms23094503

  • Doležalová A., Sládeková L., Šimoníková D., Holušová K., Karafiátová M, Varshney R. K., Doležel J. and Hřibová E. (2022) Karyotype Differentiation in Cultivated Chickpea Revealed by Oligopainting Fluorescence in situ Hybridization. Frontiers in Plant Science 12 [IF 5.6] doi: 10.3389/fpls.2021.791303

  • Prochazkova, K., Finke, A., Tomaštíková, E. D., Filo, J., Bente, H., Dvořák, P., Ovečka, M., Šamaj, J. & Pecinka, A. (2022). Zebularine induces enzymatic DNA–protein crosslinks in 45S rDNA heterochromatin of Arabidopsis nuclei. Nucleic Acids Research 50(1): 244-258 [IF2021 14.9] https://doi.org/10.1093/nar/gkab1218 
  • Ledala, N., Malik, M., Rezaul, K., Paveglio, S., Provatas, A., Kiel, A., Caimano, M., Zhou, Y., Lindgren, J., Krasulova, K., Illes, P., Dvořák, Z., Kortagere, S., Kienesberger, S., Cosic, A., Pöltl, L., Zechner, E. L., Ghosh, S., Mani, S., Radolf, J. D. & Matson, A. P. (2022). Bacterial Indole as a Multifunctional Regulator of Klebsiella oxytoca Complex Enterotoxicity. mBio: e0375221.[IF 6.4] doi.org/10.1128/mbio.03752-21

     

    2021

    • Afify, S. M., Regner, A., Pacios, L. F., Blokhuis, B. R., Jensen, S. A., Redegeld, F. A., Pali‐Schöll, I., Hufnagl, K., Bianchini, R., Guethoff, S., Kramer, M. F., Fiocchi, A., Dvorak, Z., Jensen‐Jarolim, E. & Roth‐Walter, F. (2021). Micronutritional supplementation with a holoBLG‐based FSMP (food for special medical purposes)‐lozenge alleviates allergic symptoms in BALB/c mice: Imitating the protective farm effect. Clinical & Experimental Allergy 2021;00:1–16.  [IF 5.401] https://doi.org/10.1111/cea.14050
    • Strejčková, B., Milec, Z., Holušová, K., Cápal, P., Vojtková, T., Čegan, R. & Šafář, J. (2021). In-Depth Sequence Analysis of Bread Wheat VRN1 Genes. International Journal of Molecular Sciences 22(22): 12284  [IF 6.208] https://doi.org/10.3390/ijms222212284
    • Yang, F., Fernandez-Jimenez, N., Tuckova, M., Vrana, J., Capal, P., Diaz, M., Pradillo, M. & Pecinka, A. (2021a). Defects in meiotic chromosome segregation lead to unreduced male gametes in Arabidopsis SMC5/6 complex mutants. Plant Cell 33(9): 3104-3119. Plant Cell 33(9): 3104-3119. [IF 12.085] https://doi.org/10.1093/plcell/koab178

    • Yang, F., Fernández Jiménez, N., Majka, J., Pradillo, M. & Pecinka, A. (2021b). Structural Maintenance of Chromosomes 5/6 Complex Is Necessary for Tetraploid Genome Stability in. Front Plant Sci 12: 748252.[IF 6.627] https://doi.org/10.3389/fpls.2021.748252

    • Hufnagl, K., Kromp, L., Bianchini, R., Afify, S. M., Wiederstein, M., Redegeld, F. A., Zuvalova, I., Dvorak, Z., Hofstetter, G., Roth‐Walter, F., Pacios, L. F. & Jensen‐Jarolim, E. (2021). Bet v 1 from birch pollen is a hypoallergen with vitamin D3 in the pocket. Allergy 76(12): 3801-3804 [IF 14.710]  https://doi.org/10.1111/all.15052

    • Vrzal, R. (2021). Genetic and Enzymatic Characteristics of CYP2A13 in Relation to Lung Damage. International Journal of Molecular Sciences 22(22): 12306 [IF 6.208] https://doi.org/10.3390/ijms222212306

    • Vančo, J., Trávníček, Z., Hošek, J. & Dvořák, Z. (2021). Heteroleptic copper(II) complexes of prenylated flavonoid osajin behave as selective and effective antiproliferative and anti-inflammatory agents. J Inorg Biochem 226: 111639 [IF 4.336] doi: 10.1016/j.jinorgbio.2021.111639

    • Massoud, S. S., Louka, F. R., Dial, M. T., Malek, A. J., Fischer, R. C., Mautner, F. A., Vančo, J., Malina, T., Dvořák, Z. & Trávníček, Z. (2021). Identification of potent anticancer copper(ii) complexes containing tripodal bis[2-ethyl-di(3,5-dialkyl-1H-pyrazol-1-yl)]amine moiety. Dalton Transactions. [IF 4.569] doi: 10.1039/d1dt01724a

    • Krasulova, K. & Illes, P. (2021). Intestinal interplay of quorum sensing molecules and human receptors. Biochimie 189: 108-119 [IF 4.372] doi: 10.1016/j.biochi.2021.06.010

    • Li, H., Illés, P., Karunaratne, C. V., Nordstrøm, L. U., Luo, X., Yang, A., Qiu, Y., Kurland, I. J., Lukin, D. J., Chen, W., Jiskrová, E., Krasulová, K., Pečinková, P., DesMarais, V. M., Liu, Q., Albanese, J. M., Akki, A., Longo, M., Coffin, B., Dou, V., Mani, S. & Dvořák, Z. (2021). Deciphering structural bases of intestinal and hepatic selectivity in targeting pregnane X receptor with indole-based microbial mimics. Bioorg Chem 109: 104661 [IF 5.307] doi: 10.1016/j.bioorg.2021.104661

    • Dvorak, Z., Poulikova, K. & Mani, S. (2021). Indole scaffolds as a promising class of the aryl hydrocarbon receptor ligands. Eur J Med Chem 215: 113231 [IF 7.088] https://doi.org/10.1016/j.ejmech.2021.113231

    • Roth-Walter, F., Afify, S. M., Pacios, L. F., Blokhuis, B. R., Redegeld, F., Regner, A., Petje, L. M., Fiocchi, A., Untersmayr, E., Dvorak, Z., Hufnagl, K., Pali-Schöll, I. & Jensen-Jarolim, E. (2020). Cow's milk protein β-lactoglobulin confers resilience against allergy by targeting complexed iron into immune cells. J Allergy Clin Immunol 147 (1): 321-334 [IF 14.290] https://doi.org/10.1016/j.jaci.2020.05.023

    • Zenata, O., Panacek, A., Kvitek, L. & Vrzal, R. (2021). The impact of graphene oxide on androgen receptor signalling in prostate cancer cells. Chemosphere 269  [IF 8.943] https://doi.org/10.1016/j.chemosphere.2020.128759

    • Vančo, J., Trávníček, Z., Hošek, J., Malina, T. & Dvořák, Z. (2021). Copper(II) Complexes Containing Natural Flavonoid Pomiferin Show Considerable In Vitro Cytotoxicity and Anti-inflammatory Effects. International Journal of Molecular Sciences 22(14): 7626 [IF 6.208] https://doi.org/10.3390/ijms22147626

    2020

    • Marais, A., Šafářová, D., Navrátil, M. et al. (2020) Complete genome sequence of cherry virus T, a novel cherry-infecting tepovirus. Arch Virol 165:1711–1714 [IF 2.574] https://doi.org/10.1007/s00705-020-04656-w

    • Dvorak, Z. (2020). Pelargonidin and its glycosides as dietary chemopreventives attenuating inflammatory bowel disease symptoms through the aryl hydrocarbon receptor. Eur J Nutr 59(8): 3863-3864 [IF 5.614] doi: 10.1007/s00394-020-02316-y

    • Dvorak, Z., Sokol, H. & Mani, S. (2020). Drug Mimicry: Promiscuous Receptors PXR and AhR, and Microbial Metabolite Interactions in the Intestine. Trends Pharmacol Sci. 41(12): 900-908 [IF14.819] doi: 10.1016/j.tips.2020.09.013

    • Li, H., Ranhotra, H. S., Mani, S., Dvorak, Z., Sokol, H. & Muller, R. (2020). Human microbial metabolite mimicry as a strategy to expand the chemical space of potential drugs. Drug Discov Today 25(9):1575-1579. [IF 7.851] doi: 10.1016/j.drudis.2020.06.007

    • Brtko, J. & Dvorak, Z. (2020). Natural and synthetic retinoid X receptor ligands and their role in selected nuclear receptor action. Biochimie 179: 157-168. [IF 4.709] doi:10.1016/j.biochi.2020.09.027

    • Illes, P., Krasulova, K., Vyhlidalova, B., Poulikova, K., Marcalikova, A., Pecinkova, P., Sirotova, N., Vrzal, R., Mani, S. & Dvorak, Z. (2020). Indole microbial intestinal metabolites expand the repertoire of ligands and agonists of the human pregnane X receptor. Toxicol Lett 334: 87-93. [IF 4.372] doi:10.1016/j.toxlet.2020.09.015

    • Dvorak, Z., Klapholz, M., Burris, T. P., Willing, B. P., Gioiello, A., Pellicciari, R., Galli, F., March, J., O'Keefe, S. J., Sartor, R. B., Kim, C. H., Levy, M. & Mani, S. (2020). Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs. Mol Pharmacol 98(4): 343-349. [IF 4.436] doi:10.1124/molpharm.120.000035

    • Starha, P., Hosek, J., Travnicek, Z. & Dvorak, Z. (2020). Cytotoxic dimeric half-sandwich Ru(II), Os(II) and Ir(III) complexes containing the 4,4 '-biphenyl-based bridging ligands. Applied Organometallic Chemistry 34:e5785. [IF 4.105] doi:10.1002/aoc.5785

    • Safarova, D., Sevcikova, V., Neumanova, K., Sucha, J.,Necas, T. and Navratil M. (2020)  Molecular characterisation of little cherry virus 1 infecting apricots in the Czech Republic. Eur J Plant Pathol, 158(1), 83-97 [IF 1.907] odkaz

    • Zenata, O., Vrzalova, A., Bachleda, P., Janeckova, J., Panacek, A., Kvitek, L. & Vrzal, R. (2020). The effect of graphene oxide on signalling of xenobiotic receptors involved in biotransformation. Chemosphere 253: 126753 [IF 7.086] doi:10.1016/j.chemosphere.2020.126753

    • Vyhlidalova, B., Krasulova, K., Pecinkova, P., Poulikova, K., Vrzal, R., Andrysik, Z., Chandran, A., Mani, S. & Dvorak, Z. (2020). Antimigraine Drug Avitriptan Is a Ligand and Agonist of Human Aryl Hydrocarbon Receptor that Induces CYP1A1 in Hepatic and Intestinal Cells. International Journal of Molecular Sciences 21(8):2799. [IF 5.923] doi:10.3390/ijms21082799

    • Vyhlidalova, B., Krasulova, K., Pecinkova, P., Marcalikova, A., Vrzal, R., Zemankova, L., Vanco, J., Travnicek, Z., Vondracek, J., Karasova, M., Mani, S. & Dvorak, Z. (2020). Gut Microbial Catabolites of Tryptophan Are Ligands and Agonists of the Aryl Hydrocarbon Receptor: A Detailed Characterization. International Journal of Molecular Sciences 21(7):2614. [IF 5.923] doi:10.3390/ijms21072614

    • Dvorak, Z., Kopp, F., Costello, C. M., Kemp, J. S., Li, H., Vrzalova, A., Stepankova, M., Bartonkova, I., Jiskrova, E., Poulikova, K., Vyhlidalova, B., Nordstroem, L. U., Karunaratne, C. V., Ranhotra, H. S., Mun, K. S., Naren, A. P., Murray, I. A., Perdew, G. H., Brtko, J., Toporova, L., Schon, A., Wallace, W. G., Walton, W. G., Redinbo, M. R., Sun, K., Beck, A., Kortagere, S., Neary, M. C., Chandran, A., Vishveshwara, S., Cavalluzzi, M. M., Lentini, G., Cui, J. Y., Gu, H. W., March, J. C., Chatterjee, S., Matson, A., Wright, D., Flannigan, K. L., Hirota, S. A., Sartor, R. B. & Mani, S. (2020). Targeting the pregnane X receptor using microbial metabolite mimicry. Embo Molecular Medicine 12(4):e11621. [IF 12.137] doi:10.15252/emmm.201911621

    • Vyhlidalova, B., Bartonkova, I., Jiskrova, E., Li, H., Mani, S. & Dvorak, Z. (2020). Differential activation of human pregnane X receptor PXR by isomeric mono-methylated indoles in intestinal and hepatic in vitro models. Toxicology Letters 324: 104-110. [IF 4.372] doi: 10.1016/j.toxlet.2020.02.010

    2019

    • Massart S., Adams I., De Jonghe K., Chiumenti M., Koloniuk I., Komínek P., Kreuze J., Kutnjak D., Lotos L., Maree H., Olivier T., Olmos A., Pooggin M., Ruiz-García A., Šafářová D., Schneeberger P., Sela N., Turco S., Varallyay E., Vainio E., Verdin E., Westenberg M., Brostaux Y., Candresse T. (2019): Virus detection by high-throughput sequencing of small RNAs: large scale performance testing of sequence analysis strategies. Phytopathology 109 (3):488-497 [IF 3.234]

    • Vyhlídalová B., Poulíková K., Bartoňková I., Krasulová K., Vančo J., Trávníček Z., Mani S. and Z. Dvořák (2019). Mono-methylindoles induce CYP1A genes and inhibit CYP1A1 enzyme activity in human hepatocytes and HepaRG cells.  Toxicology Letters 313: 66-76 [IF 3.569]

    • Pěnčíková K., M. Ciganek, J. Neča, P. Illes, Z. Dvořák, J. Vondráček and M. Machala (2019). Modulation of endocrine nuclear receptor activities by polyaromatic compounds present in fractionated extracts of diesel exhaust particles. Sci Total Environ 677: 626-636 [IF 6.551]

    • Massoud S., F. Louka, A. Tusa, N. Bordelon, R. Fisher, F. Mautner, J. Vančo, J. Hošek, Z. Dvořák and Z. Trávníček (2019). Copper(II) complexes based on tripodal pyridyl amine derivatives as efficient anticancer agents. New J. Chem 43:6186.  [IF 3.288]

    • Starha, P., Z. Travnicek, J. Vanco and Z. Dvorak (2019). In vitro anticancer active cis-Pt(II)-diiodido complexes containing 4-azaindoles. J Biol Inorg Chem 24(2): 257-269.  [IF 3.246]

    • Travnicek, Z., P. Starha, M. Cajan, Z. Dvorak (2019) A half-sandwich TaV dichlorido complex containing an O,N,O -tridentate Schiff base ligand: synthesis, crystal structure and in vitro cytotoxicity. Acta Crystallogr C Struct Chem 75(Pt 3):248-254. [IF 1.090]

    • Abbott, K. L., C. S. Chaudhury, A. Chandran, S. Vishveshwara, Z. Dvorak, E. Jiskrova, K. Poulikova, B. Vyhlidalova, S. Mani and S. R. Pondugula (2019). Belinostat, at Its Clinically Relevant Concentrations, Inhibits Rifampicin-Induced CYP3A4 and MDR1 Gene Expression. Mol Pharmacol 95(3): 324-334 [IF 3.664]

    • Hyrsova L., Vanduchova A., Dusek J., Smutny T., Carazo A., Maresova V., Trejtnar F., Barta P., Anzenbacher P., Dvorak Z., Pavek P. (2019) Trans-resveratrol, but not other natural stilbenes occurring in food, carries the risk of drug-food interaction via inhibition of cytochrome P450 enzymes or interaction with xenosensor receptors. Toxicology Letters, 300, 81-91 [IF 3.569]

    • Krasulova, K., Z. Dvorak and P. Anzenbacher (2019). In vitro analysis of itraconazole cis-diastereoisomers inhibition of nine cytochrome P450 enzymes: stereoselective inhibition of CYP3A. Xenobiotica 49(1): 36-42. [IF 1.902]

2018

  • Illés P., Grycová A., Krasulová K. Dvořák Z. (2018) Effects of Flavored Nonalcoholic Beverages on Transcriptional Activities of Nuclear and Steroid Hormone Receptors: Proof of Concept for Novel Reporter Cell Line PAZ-PPARg. J. Agric. Food Chem 66: 12066−12078 [IF 3.571]

  • Ahmad S., Altoum A., Vančo J., Křikavová R., Trávníček Z., Dvořák Z., Altaf M., Sohail M., Isab A. (2018): Synthesis, crystal structure and anticancer activity of tetrakis(N-isopropylimidazolidine-2-selenone)platinum(II) chloride. Journal of Molecular Structure 1152: 232 - 236. [IF 2.120]

  • Šafářová D., Candresse T., Navrátil M. (2018): Complete genome sequence of a novel bromovirus infecting elderberry (Sambucus nigra L.) in the Czech Republic. Archives of virology 163:567 - 570. [IF 2.261]

  • Bartoňková I., Dvořák Z. (2018): Essential oils of culinary herbs and spices display agonist and antagonist activities at human aryl hydrocarbon receptor AhR. Food and Chemical Toxicology 111: 374 - 384. [IF 3.775]

  • Massoud S., Louka F., Ducharme G., Fisher R., Mautner F., Vančo J., Herchel R., Dvořák Z., Trávníček Z. (2018): Copper(II) complexes based on tripodal pyrazolyl amines: Synthesis, structure, magnetic properties and anticancer activity. Journal of Inorganic Biochemistry 180: 39 - 46. [IF 3.224]

  • Štarha P., Trávníček Z., Drahoš B., Herchel R., Dvořák Z. (2018): Cell-based studies of the first-in-class half-sandwich Ir(III) complex containing histone deacetylase inhibitor 4-phenylbutyrate. Applied Organometallic Chemistry 32: e4246. [IF 3.259]

  • Štarha P., Trávníček Z., Vančo J., Dvořák Z. (2018): Half-sandwich Ru(II) and Os(II) bathophenanthroline complexes containing a releasable dichloroacetato ligand. Molecules 23: 420. [IF 3.060]

  • Bartoňková I., Kallay E., Dvořák Z. (2018): Effects of human interleukins in the transgenic gene reporter cell lines IZ-VDRE and IZ-CYP24 designed to assess the transcriptional activity of vitamin D receptor. PLoS ONE 12: e0193655. [IF 2.776]

  • Pěnčíková K., Svržková L., Strapáčová S., Neča J., Bartoňková I., Dvořák Z., Hýžďalová M., Pivnička J., Pálková L., Lehmler H., Li X., Vondráček J., Machala M. (2018): In vitro profiling of toxic effects of prominent environmental lower-chlorinated PCB congeners linked with endocrine disruption and tumor promotion. Environmental Pollution 237: 473 - 486. [IF 5.714]

  • Šafářová D., Lauterer P., Starý M., Válová P., Navrátil M. (2018): Insight into epidemiological importance of planthoppers, leafhoppers, and other phytoplasma vectors in vineyards in South Moravia, Czech Republic. Plant Protection Science 54: 234-239,  [IF 1.464]

  • Štarha P., Trávníček Z., Herchel R., Jewula P., Dvořák Z. (2018): A potential method to improve the in vitro cytotoxicity half-sandwich Os(II) complexes against A2780 cells. Dalton Transaction, 47, 5714 - 5724. [IF 1.464]

  • Bartoňková I., Dvořák Z. (2018): Assessment of endocrine disruption potential of essential oils of culinary herbs and spices involving glucocorticoid, androgen and vitamin D receptors. Food and Function 9: 2136 - 2144. [IF 3.241]

  • Ženata O., Dvořák Z., Vrzal R. (2018): Mycophenolate Mofetil induces c-Jun-N-terminal kinase expression in 22Rv1 cells: an impact on androgen receptor signaling. Journal of Cancer 9: 1915 - 1924. [IF 3.241]

  • Ženata O., Dvořák Z., Vrzal R. (2018): Pharmacologically relevant concentrations of berberine transiently stimulate dihydrotestosterone-inducible androgen receptor-mediated luciferase activity in human prostate cancer cells. Translational Cancer Research 7: 383 - 390. [IF 1.070]

  • Štěpánková M., Bartoňková I., Jiskrová E., Vrzal R., Mani S., Kortagere S., Dvořák Z. (2018): Methylindoles and methoxyindoles are agonists and antagonists of human Aryl hydrocarbon receptor. Molecular Pharmacology 93: 631 - 644. [IF 3.853]

  • Šafářová D., Vavroušková K., Candresse T., Navrátil M. (2018): Molecular characterization of novel Aureusvirus infecting elderberry Sambucus nigra L. PLoS ONE 13(8):e0200506,  [IF 2.776]

  • Massart S., Adams I., De Jonghe K., Chiumenti M., Koloniuk I., Komínek P., Kreuze J., Kutnjak D., Lotos L., Maree H., Olivier T., Olmos A., Pooggin M., Ruiz-García A., Šafářová D., Schneeberger P., Sela N., Turco S., Varallyay E., Vainio E., Verdin E., Westenberg M., Brostaux Y., Candresse T. (2018): Virus detection by high-throughput sequencing of small RNAs: large scale performance testing of sequence analysis strategies. Phytopathology 109(3):488-497. [IF 3.264]

  • Štarha P., Dvořák Z., Trávníček Z. (2018): Half-sandwich Ir(III) and Rh(III) 2,2´-dipyridylamine complexes: Synthesis, characterization and in vitro cytotoxicity against the ovarian carcinoma cells. Journal of Organometallic Chemistry 872: 144 - 122. [IF 2.066]

  • Bartoňková I., Dvořák Z. (2018): Essential oils of culinary herbs and spices activate PXR and induce CYP3A4 in human intestinal and hepatic in vitro models. Toxicology Letters 296: 1 - 9. [IF 3.499]

  • Štarha P., Trávníček Z., Dvořák Z. (2018): A cytotoxic tantalum(V) half-sandwich complex: a new challenge for metal-based anticancer agents. Chem. Commun. 54: 9533. [IF2018 6.164]

  • Štarha P., Trávníček Z., Crlíková H., Vančo J., Kašpárková J., Dvořák Z. (2018): Half-sandwich Ir(III) complexes of N1-pyridyl-7-azaindole exceeds cytotoxicity of cisplatin at various human cancer cells and 3D multicellular tumor spheroids. Organometallics 37: 2749 - 2759. [IF 4.1]

  • Toporová L., Illés P., Dvořák Z., Bobal P., Otevrel J., Brtko J. (2018): Effects of selected triorganotin compounds on transcriptional activity of vitamin D3 receptor and peroxisome proliferator-activated receptor gamma. General Physiology and Biophysics 37: 589 - 596. [IF 1.309]

  • Pastorková B., Illés P., Dvořák Z. (2018): Profiling of anthosyanidins against transcriptional activities of steroid and nuclear receptors. Drug and Chemical Toxicology 41: 434 - 440. [IF 1.946]

2017

[Translate to en:]

  • Černá H., Černý M., Habánová H., Šafářová D., Abushamsya K., Navrátil M., Brzobohatý B. (2017): Proteomics offers insight to the mechanism behind Pisum sativum L. response to pea seed-borne mosaic virus (PSbMV). Journal of Proteomics, 153, 78 - 88. [IF2014 3.888]

  • Vrzalová A., Theile D., Weiss J., Vrzal R. (2017): Differential effects of the enantiomers of tamsulosin and tolterodine on P-glycoprotein and cytochrome P450 3A4. Naunyn Schmiedebergs Arch Pharmacol., 390, 49 - 59. [IF2015 2.376]

  • Vondráček J., Pěnčíková K., Neča J., Ciganek M., Grycová A., Dvořák Z., Machala M. (2017): Assessment of the aryl hydrocarbon receptor-mediated activities of polycyclic aromatic hydrocarbons in human cell-based reporter gene assay. Environmental Pollution, 220, 307 - 316. [IF2015 4.839]

  • Pastorková B., Vrzalová A., Bachleda P., Dvořák Z. (2017): Hydroxystilbenes and methoxystilbenes activate human aryl hydrocarbon receptor and induce CYP1A genes in human hepatoma cells and human hepatocytes. Food and Chemical Toxicology, 103, 122 - 132. [IF2015 3.584]

  • Altoum A., Vančo J., Křikavová R., Trávníček Z., Dvořák Z., Altaf M., Ahmad S., Sulaiman A., Isab A. (2017): Synthesis, structural characterization and cytotoxicity evaluation of platinum(II) complexes of heterocyclic selenones. Polyhedron, 128, 2 - 8. [IF2015 2.108]

  • Yar M., Shahzadi L., Farooq A., Imram S., Cerón-Carrasco J., den-Haan H., Kumar S., Pena-García J., Pérez-Sánchez H., Grycová A., Dvořák Z., Vrzal R. (2017): In vitro modulatory effects of functionalized pyrimidines and piperidine derivatives on Aryl hydrocarbon receptor (AhR) and glucocorticoid receptor (GR) activities. Bioorganic Chemistry, 71, 285 - 293. [IF2015 2.252]

  • Roth-Walter F., Bergmayr C., Meitz S., Buchleitner S., Stremnitzer C., Fazekas J., Moskovskich A., Müller M., Roth G., Manzano-Szalai K., Dvořák Z., Neunkirchner A., Jensen-Jarolim E. (2017): Janus-faced Acrolein prevents allergy but accelerates tumor growth by promoting immunoregulatory Foxp3+ cells: Mouse model for passive respiratory exposure. Scientific Reports, 7, 45067. [IF2015 5.228]

  • Štěpánková M., Pastorková B., Bachleda P., Dvořák Z. (2017): Itraconazole cis-diastereoisomers activate aryl hydrocarbon receptor AhR and pregnane X receptor PXR and induce CYP1A1 in human cell lines and human hepatocytes. Toxicology, 383, 40 - 49. [IF2015 3.817]

  • Vrzal R., Vrzalová A., Grycová A., Dvořák Z. (2017): Activated thyroid hormone receptor modulates dioxin-inducible aryl hydrocarbon receptor-mediated CYP1A1 induction in human hepatocytes but not in human hepatocarcinoma HepG2 cells. Toxicology Letters, 275, 77 - 82. [IF2015 3.522]

  • Ženata O., Vrzal R. (2017): Fine tuning of vitamin D receptor (VDR) activity by post-transcriptional and post-translational modifications. Oncotarget, 8, 35390 - 35402. [IF2015 5.008]

  • Špak J., Přibylová J., Šafářová D., Lenz O., Koloniuk I., Navrátil M., Fránová J., Špaková V., Paprštein F. (2017): Cherry necrotic rusty mottle and Cherry green ring mottle viruses in Czech cherry germplasm. Plant Protection Science, 53, 195 - 200. [IF2015 0.661]

  • Šafářová D., Faure C., Candresse T., Navrátil M., Nečas T., Marais A. (2017): First report of Little cherry virus 1 infecting apricot in the Czech Republic. Plant Disease, 101, 845. [IF2015 3.192]

  • Šafářová D., Faure C., Marais A., Suchá J., Paprštein F., Navrátil M., Candresse T. (2017): First report of Prunus virus F infecting sour cherry in the Czech Republic. Plant Disease, 101, 1828. [IF2015 3.192]

  • Vančo J., Trávníček Z., Křikavová R., Gáliková J., Dvořák Z., Chalupová M. (2017): Molecular, cellular and pharmacological effects of platinum(II) diiodido complexes containing 9-deazahypoxanthine derivatives: A group of broad-spectrum anticancer active agents. Journal of Photochemistry and Photobiology, B: Biology, 173, 423 - 433. [IF2016 2.673]

  • Dvořák Z. (2017): Involvement of aryl hydrocarbon receptor (AhR) in polyphenol inhibition of benzo[a]pyrene-induced oxidative stress and neoplastic transformation. Food and Chemical Toxicology, 107, 523 - 525. [IF2016 3.778]

  • Šafářová D., Neoralová V., James D., Navrátil M. (2017): Almond (Prunus dulcis L.) - not a natural host of Plum pox virus in the Czech Republic. Acta Horticulturae (ISHS), 1163, 123 - 128.

  • Skrott Z., Mistrík M., Andersen K., Friis S., Majera D., Sedláček J., Hajduch M , Cvek B., Deshaies R., Bartek J., et al., (2017): Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4. Nature, 552, 194 - 199. [IF2016 40.137]

2016

  • Krasulová K., Siller M., Holas O., Dvořák Z., Anzenbacher P. (2016): Enantiospecific effects of chiral drugs on cytochrome P450 inhibition in vitro. Xenobiotica, 46, 315 - 324. [IF2014 2.199]

  • Křikavová R., Vančo J., Trávníček Z., Buchtík R., Dvořák Z. (2016): Copper(II) quinolinonato-7-carboxamido complexes as potent antitumor agents with broad spectrum and selective effects. RSC Adv, 6, 3899 - 3909. [IF2014 3.840]

  • Dvořák Z. (2016): Opportunities and challenges in using human hepatocytes in cytochrome P450 induction assays. Expert Opin Drug Metab Toxicol, 12, 169 - 174. [IF2014 2.831]

  • Pasquel D., Vrzalová (Dořičáková) A., Li H., Kortagere S., Krasowski M., Biswas A., Walton W., Redinbo M., Dvořák Z., Mani S. (2016): Acetylation of Lysine 109 Modulates Pregnane X Receptor DNA Binding and Transcriptional Activity. BBA - Gene Regulatory Mechanisms. [IF2014 6.332]

  • Vrzal R. (2016): Anthocyanidins but not anthocyanins inhibit P-glycoprotein-mediated calcein extrusion – possible implication for orally administered drugs. Fundamental & Clinical Pharmacology, 30, 248 - 252. [IF2014 2.121]

  • Dvořák Z. (2016): Pivotal role of the aryl hydrocarbon receptor in modulations caused by benzo[a]pyrene and ketoconazole in the estrogenic responses induced by 17β-estradiol in male goldfish. Environ Sci Pollut Res, 23, 9247 - 9248. [IF2014 2.828]

  • Šafářová D., Zemánek T., Válová P., Navrátil M. (2016): ‘Candidatus Phytoplasma cirsii’, a novel taxon from creeping thistle [Cirsium arvense (L.) Scop.]. International Journal of Systematic and Evolutionary Microbiology, 66, 1745 - 1753. [IF2014 2.511]

  • Kubešová K., Vrzalová (Dořičáková) A., Trávníček Z., Dvořák Z. (2016): Mixed-ligand copper(II) complexes activate aryl hydrocarbon receptor AhR and induce CYP1A genes expression in human hepatocytes and human cell lines. Toxicology Letters, 255, 24 - 35. [IF2014 3.262]

  • Kubešová K., Trávníček Z., Dvořák Z. (2016): Pleiotropic effects of gold(I) mixed-ligand complexes of 9- deazahypoxanthine on transcriptional activity of receptors for steroid hormones, nuclear receptors and xenoreceptors in human hepatocytes and cell lines. European Journal of Medicinal Chemistry, 121, 530 - 540. [IF2015 3.902]

  • Vrzal R., Illés P., Dvořák Z. (2016): Transplant drugs affect the expression of phase II and antioxidant enzymes in human carcinoma cells HepG2 but not in primary cultures of human hepatocytes: In vitro comparative study. Pharmacological Reports, 68, 1008 - 1014. [IF2015 2.251]

  • Bartoňková I., Grycová (Novotná) A., Dvořák Z. (2016): Profiling of Vitamin D Metabolic Intermediates toward VDR Using Novel Stable Gene Reporter Cell Lines IZ-VDRE and IZ-CYP24. Chem Res Toxicol, 29, 1211 - 1222. [IF2015 3.025]

  • Křikavová R., Vančo J., Trávníček Z., Hutyra J., Dvořák Z. (2016): Design and characterization of highly in vitro antitumor active ternary copper(II) complexes containing 2′-hydroxychalcone ligands. Journal of Inorganic Biochemistry, 163, 8 - 17. [IF2015 3.205]

  • Štarha P., Trávníček Z., Pazderová L., Dvořák Z. (2016): Platinum(II) carboxylato complexes containing 7 azaindoles as N-donor carrier ligands showed cytotoxicity against cancer cell lines. Journal of Inorganic Biochemistry, 162, 109 - 116. [IF2015 3.205]

  • Vrzal R., Dvořák Z. (2016): The comparative effects of diethyldithiocarbamate-copper complex with established proteasome inhibitors on expression levels of CYP1A2/3A4 and their master regulators, aryl hydrocarbon (AhR) and pregnane X receptor (PXR) in primary cultures of human hepatocytes. Fundamental & Clinical Pharmacology, 30, 585 - 595. [IF2015 2.156]

  • Šafářová D., Starý M., Válová P., Opatíková M., Bílková L., Navrátil M. (2016): Impact of insecticides treatment on phytoplasma infection risk in apple orchards. HORTICULTURAL SCIENCE, 43, 112 - 116. [IF2015 0.436]

  • Herchel R., Dvořák Z., Trávníček Z., Mikuriya M., Louka F., Mautner F., Massoud S. (2016): Cobalt(II) and copper(II) covalently and non-covalently dichlorido-bridged complexes of an unsymmetrical tripodal pyrazolyl-pyridyl amine ligand: Structures, magnetism and cytotoxicity. Inorganica Chimica Acta, 451, 102 - 110. [IF2015 1.918]

  • Raclavský V., Stromerová N., Šafářová D., Bardon J., Zatloukal J., Zápalka M., Jakubec P., Navrátilová L., Novotný R. (2016): McRAPD unlike MALDI-TOF MS is a suitable candidate for routine discrimination of new Haemophilus influenzae strain acquisition in chronic obstructive pulmonary disease (COPD) and cystic fibrosis. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub, 160, 503 - 511. [IF2015 0.924]

  • Štarha P., Vančo J., Trávníček Z., Hošek J., Klusáková J., Dvořák Z. (2016): Platinum(II) Iodido Complexes of 7-Azaindoles with Significant Antiproliferative Effects: An Old Story Revisited with Unexpected Outcomes. PLoS ONE, 11, e0165062. [IF2015 3.057]

  • Štarha P., Trávníček Z., Drahoš B., Dvořák Z. (2016): In Vitro Antitumor Active Gold(I) Triphenylphosphane Complexes Containing 7-Azaindoles. International Journal of Molecular Science, 17, 2084. [IF2015 3.257]

  • Štěpánková (Korhoňová) M., Krasulová K., Vrzalová (Dořičáková) A., Kurka O., Anzenbacher P., Dvořák Z. (2016): Optical isomers of dihydropyridine calcium channel blockers display enantiospecific effects on the expression and enzyme activities of human xenobiotics-metabolizing cytochromes P450. Toxicology Letters, 262, 173 - 186. [IF2015 3.522]

  • Štarha P., Trávníček Z., Křikavová R., Dvořák Z. (2016): Half-Sandwich Ru(II) Halogenido, Valproato and 4-Phenylbutyrato Complexes Containing 2,2´-Dipyridylamine: Synthesis, Characterization, Solution Chemistry and In Vitro Cytotoxicity. Molecules, 21, 1725. [IF2015 2.465]

2015

  • Vančo J. , Šindelář Z. , Dvořák Z. , Trávníček Z. : (2015) Iron-salophen complexes involving azole-derived ligands: A new group of compounds with high-level and broad-spectrum in vitro antitumor activity. Journal of Inorganic Biochemistry . 142. 92 - 100 [IF20143.444]
  • Šafářová D. : (2015) Proceedings of the Second International Symposium on Plum Pox Virus. Acta Horticulturae. 1063. [IF]
  • Navrátil M. , Šafářová D. : (2015) An overview of Sharka and its research in the Czech Republic. Acta Horticulturae. 1063. 21 - 28 [IF] Myjavcova M. , Bednar P. , Srovnalová A. , Dvořák Z. , Papouskova B. : (2015) Ultra‐Performance Liquid Chromatography/Mass Spectrometry Study of Metabolism of 5‐Methylpyranopelargonidin. Chromatographia. 78. 189 - 201 [IF20141.411]
  • Riha J. , Brenner S. , Srovnalová A. , Klameth L. , Dvořák Z. , Jäger W. , Thalhammer T. : (2015) Effects of anthocyans on the expression of organic anion transporting polypeptides (SLCOs/OATPs) in primary human hepatocytes.. Food & Function. 6. 772 - 779 [IF20142.791]
  • Sedláček J. , Švécarová M. : (2015) Metody stanovení aktivity proteasomu a jejich aplikace. Chem. Listy. 109. 198 - 203 [IF20140.272]
  • Křikavová R. , Hanousková L. , Dvořák Z. , Trávníček Z. : (2015) Dichlorido-platinum(II) complexes with kinetin derivatives as promising cytotoxic agents avoiding resistance of cancer cells: Contrasting results between cisplatin and oxaliplatin analogues . Polyhedron. 90. 7 - 17 [IF20142.011]
  • Brtko J. , Dvořák Z. : (2015) Triorganotin compounds - ligands for "rexinoid" inducible transcription factors: Biological effects. Toxicol. Lett. 234. 50 - 58 [IF20143.262]
  • Srovnalová A. , Vanduchová A. , Švécarová M. , Anzenbacherová E. , Tománková V. , Anzenbacher P. , Dvořák Z. : (2015) Effects of sulforaphane and its S- and R- enantiomers on the expression and activities of human drug-metabolizing cytochromes P450. J Funct Foods. 14. 487 - 501 [IF20153.574]
  • Bartoňková I. , Grycová (Novotná) A. , Dvořák Z. : (2015) Novel stably transfected human reporter cell line AIZ-AR as a tool for an assessment of human androgen receptor transcriptional activity. PLOS ONE. 10. 121316 - 121316 [IF20143.234]
  • Sedláček J. : (2015) Is chemo-preventive effect of Apium leptophyllum (Pers.) caused only by anti-oxidative property of fl avonoids?. Indian Journal of Pharmacology. 47. 341 - 342 [IF20140.691]
  • Vrzal R. , Ženata O. , Bachleda P. , Dvořák Z. : (2015) The effects of drugs with immunosuppressive or immunomodulatory activities on xenobiotics-metabolizing enzymes expression in primary human hepatocytes. Toxicology in Vitro. 29. 1088 - 1099 [IF20142.903]
  • Bialesová L. , Grycová (Novotná) A. , Macejova D. , Brtko J. , Dvořák Z. : (2015) Agonistic effect of selected isoflavones on arylhydrocarbon receptor in a novel AZ-AhR transgenic gene reporter human cell line. Gen. Physiol. Biophys. . 34. 331 - 334 [IF20141.173]
  • Štarha P. , Trávníček Z. , Dvořák Z. , Radosova-Muchova T. , Pracharova J. , Vančo J. , Kašpárková J. : (2015) Potentiating effect of UVA irradiation on anticancer activity of carboplatin derivatives involving 7-azaindoles. PLOS ONE. 10. 123595 - 123595 [IF20143.234]
  • Svobodová J. , Kabátková M. , Šmerdová L. , Brenerová P. , Dvořák Z. , Machala M. , Vondráček J. : (2015) The aryl hydrocarbon receptor-dependent disruption of contact inhibition in rat liver WB-F344 epithelial cells is linked with induction of survivin, but not with inhibition of apoptosis. Toxicology. 333. 37 - 44 [IF20143.621]
  • Illés P. , Brtko J. , Dvořák Z. : (2015) Development and Characterization of a Human Reporter Cell Line for the Assessment of Thyroid Receptor Transcriptional Activity: A Case of Organotin Endocrine Disruptors.. J Agric Food Chem. 63. 7074 - 7083 [IF20142.912]
  • Vrzal R. , Ženata O. , Vrzalová (Dořičáková) A. , Dvořák Z. : (2015) Environmental pollutants parathion, paraquat and bisphenol A show distinct effects towards nuclear receptors-mediated induction of xenobiotics-metabolizing cytochromes P450 in human hepatocytes.. Toxicol Lett.. 238. 43 - 53 [IF20143.262]
  • Štarha P. , Dvořák Z. , Trávníček Z. : (2015) Highly and Broad-Spectrum In Vitro Antitumor Active cis-Dichloridoplatinum(II) Complexes with 7-Azaindoles. Plos One. 10. 136338 - 136338 [IF20143.234]
  • Vrzalová (Dořičáková) A. , Vrzal R. : (2015) A food contaminant ochratoxin A suppresses pregnane X receptor (PXR)-mediated CYP3A4 induction in primary cultures of human hepatocytes. Toxicology. 337. 72 - 78 [IF20143.621]
  • Štěpánková (Korhoňová) M. , Vrzalová (Dořičáková) A. , Dvořák Z. : (2015) Optical Isomers of Atorvastatin, Rosuvastatin and Fluvastatin Enantiospecifically Activate Pregnane X Receptor PXR and Induce CYP2A6, CYP2B6 and CYP3A4 in Human Hepatocytes.. PlosOne. 10. 137720 - 137720 [IF20143.234]
  • Grycová (Novotná) A. , Vrzalová (Dořičáková) A. , Dvořák Z. : (2015) Impurities contained in antifungal drug ketoconazole are potent activators of human aryl hydrocarbon receptor. Toxicology Letters. 239. 67 - 72 [IF20143.262]
  • Altaf M. , Isab A. , Vančo J. , Dvořák Z. , Trávníček Z. , Stoeckli-Evans H. : (2015) Synthesis, characterization and in vitro cytotoxicity of gold(III) dialkyl/diaryldithiocarbamato complexes. RSC Adv. 5. 81599 - 816007 [IF20143.840]
  • Imram S. , Ferretti P. , Vrzal R. : (2015) Different regulation of aryl hydrocarbon receptor-regulated genes in response to dioxin in undifferentiated and neuronally differentiated human neuroblastoma SH-SY5Y cells. Toxicology Mechanisms and Methods. 25. 689 - 697 [IF20141.517]

2014

  • Grycová (Novotná) A. , Kameníčková A. , Pečová M. , Štěpánková (Korhoňová) M. , Bartoňková I. , Dvořák Z. : (2014) Profiling of enantiopure drugs towards aryl hydrocarbon (AhR), glucocorticoid (GR) and pregnane X (PXR) receptors in human reporter cell lines. Chemico-Biological Interactions. 208. 64 - 76 [IF20132.982]
  • Srovnalová A. , Švécarová M. , Kopečná Zapletalová M. , Anzenbacher P. , Bachleda P. , Anzenbacherová E. , Dvořák Z. : (2014) Effects of anthocyanidins and anthocyanins on the expression and catalytic activities of CYP2A6, CYP2B6, CYP2C9, and CYP3A4 in primary human hepatocytes and human liver microsomes. Journal of Agricultural and Food Chemistry. 62. 789 - 797 [IF20133.107]
  • Štarha P. , Hošek J. , Vančo J. , Dvořák Z. , Suchý P. , Popa I. , Pražanová G. , Trávníček Z. : (2014) Pharmacological and molecular effects of platinum(II) complexes involving 7-azaindole derivatives. PLoS One. 9. 90341 - 90341 [IF20133.534]
  • Konečná E. , Šafářová D. , Navrátil M. , Hanáček P. , Coyne C. , Flavell A. , Vishnyakova M. , Redden R. , Ambrose M. , Smýkal P. : (2014) Geographical gradient of the eIF4E alleles conferring resistance to potyviruses in pea (Pisum) germplasm. PLoS One. 9. 90394 - 90394 [IF20133.534]
  • Šafářová D. , Navrátil M. : (2014) Genetic variability of the Czech Pea enation mosaic virus isolates. Czech Journal of Genetics and Plant Breeding. 2. 100 - 104 [IF20130.486]
  • Šafářová D. , Brázda P. , Navrátil M. : (2014) Effect of artificial dsRNA on infection of pea plants by Pea seed-borne mosaic virus. Czech Journal of Genetics and Plant Breeding. 2. 105 - 108 [IF20130.486]
  • Ženata O. , Vlčko T. : (2014) Potencial synergy in vitamin C and D action against diseases of viral origin. International Journal of Pharmaceutical Science and Health Care. 2. 84 - 87 [IF]
  • Dvořák Z. : (2014) Anthocyanidins pelargonidin and cyanidin reduce genotoxic stress in mice – Possible involvement of aryl hydrocarbon receptor in the process. Environmental Toxicology and Pharmacology. 37. 1129 - 1130 [IF20131.862]
  • Grycová (Novotná) A. , Srovnalová A. , Švécarová M. , Štěpánková (Korhoňová) M. , Bartoňková I. , Dvořák Z. : (2014) Differential effects of omeprazole and lansoprazole enantiomers on aryl hydrocarbon receptor in human hepatocytes and cell lines. PLoS One. 9. 98711 - 98711 [IF20133.534]
  • Smutný T. , Bitman M. , Urban M. , Dubecká M. , Vrzal R. , Dvořák Z. , Pávek P. : (2014) U0126, a mitogen‑activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up‑regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells. Archives of Toxicology. 12. 2243 - 2259 [IF20135.078]
  • Škrott Z. , Cvek B. : (2014) Linking the activity of bortezomib in multiple myeloma and autoimmune diseases. Critical Reviews in Oncology/Hematology. 2. 61 - 70 [IF20134.046]
  • Grycová (Novotná) A. , Štěpánková (Korhoňová) M. , Bartoňková I. , Soshilov A. , Denison M. , Bogdanová K. , Kolář M. , Bednář P. , Dvořák Z. : (2014) Enantiospecific effects of ketoconazole on aryl hydrocarbon receptor. PLoS One. 9. 101832 - 101832 [IF20133.534]
  • Dvořák Z. , Srovnalová A. , Švécarová M. , Vrzal R. : (2014) The effect of anthocyans on the expression of selected phase II xenobiotic-metabolizing enzymes in primary cultures of human hepatocytes. Food & Function. 9. 2145 - 2151 [IF20132.907]
  • Štarha P. , Trávníček Z. , Popa I. , Dvořák Z. : (2014) Synthesis, Characterization and in Vitro Antitumor Activity of Platinum(II) Oxalato Complexes Involving 7-Azaindole Derivatives as Coligands. Molecules. 19. 10832 - 10844 [IF20132.095]
  • Grycová (Novotná) A. , Dvořák Z. : (2014) Omeprazole and lansoprazole enantiomers induce CYP3A4 in human hepatocytes and cell lines via glucocorticoid receptor and pregnane X receptor axis. PLoS One. 9. 105580 - 105580 [IF20143.234]
  • Křikavová R. , Hošek J. , Vančo J. , Hutyra J. , Dvořák Z. , Trávníček Z. : (2014) Gold(I)-Triphenylphosphine Complexes with Hypoxanthine-Derived Ligands: In Vitro Evaluations of Anticancer and Anti-Inflammatory Activities. PLOS ONE. 9. 107373 - 107373 [IF20143.234]
  • Vančo J. , Gáliková J. , Hošek J. , Dvořák Z. , Paráková L. , Trávníček Z. : (2014) Gold(I) Complexes of 9-Deazahypoxanthine as Selective Antitumor and Anti-Inflammatory Agents. PLOS ONE. 9. 109901 - 109901 [IF20143.234]
  • Grycová (Novotná) A. , Krasulová K. , Bartoňková I. , Štěpánková (Korhoňová) M. , Bachleda P. , Anzenbacher P. , Dvořák Z. : (2014) Dual effects of ketoconazole cis-enantiomers on CYP3A4 in human hepatocytes and HepG2 cells.. PLoS ONE. 9. 111286 - 111286 [IF20143.234]
  • Sedláček J. , Martins L. , Daněk P. , Pombeiro A. , Cvek B. : (2014) Diethyldithiocarbamate complexes with metals used as food supplements show different effects in cancer cells. Journal of applied biomedicine. 12. 301 - 308 [IF20131.775]
  • Weiss J. , Theile D. , Dvořák Z. , Haefeli W. : (2014) Interaction Potential of the Multitargeted Receptor Tyrosine Kinase Inhibitor Dovitinib with Drug Transporters and Drug Metabolising Enzymes Assessed in Vitro. Pharmaceutics. 6. 632 - 650 [IF]
  • Rohozková J. , Šebela M. , Navrátil M. : (2014) P1 peptidase of Pea seed-borne mosaic virus contains non-canonical C2H2 zinc finger and may act in a truncated form. Journal of Plant Science & Molecular Breeding. 3. [IF]

2013

  • Dořičáková A. , Grycová (Novotná) A. , Vrzal R. , Pávek P. , Dvořák Z. : (2013) The role of residues T248, Y249 and T422 in the function of human pregnane X receptor. Archives of Toxicology. 87. 291 - 301 [IF20135,078]
  • Kameníčková A. , Anzenbacherová E. , Pávek P. , Soshilov A. , Denison M. , Anzenbacher P. , Dvořák Z. : (2013) Pelargonidin activates the AhR and induces CYP1A1 in primary human hepatocytes and human cancer cell lines HepG2 and LS174T. Toxicology Letters. 218. 253 - 259 [IF20133,355]
  • Cvek B. : (2013) Comment on 'Cytotoxic effect of disulfiram/copper on human glioblastoma cell lines and ALDH-positive cancer-stem-like cells'. British Journal of Cancer. 108. 993 - 993 [IF20134,817]
  • Trávníček Z. , Popa I. , Dvořák Z. , Štarha P. : (2013) N-(2-Methoxybenzyl)-9-(oxolan-2-yl)-9H-purin-6-amine. Acta Crystallographica. E69. 588 - 588 [IF]
  • Štarha P. , Popa I. , Dvořák Z. , Trávníček Z. : (2013) 6-(3,5-Dimethoxybenzylamino)-9-(oxan-2-yl)-9H-purine. Acta Crystallographica. E69. 533 - 533 [IF]
  • Stejskalová L. , Vrzal R. , Rulcová A. , Dvořák Z. , Pávek P. : (2013) Effects of glucocorticoids on cytochrome P450 1A1 (CYP1A1) expression in isolated human placentla trophoblast. Journal of Applied Biomedicine. 11. 163 - 172 [IF20131,775]
  • Kennedy M. , Taylor S. , Nádvorník P. , Spencer H. : (2013) The phylogenetic relationships of the extant pelicans inferred from DNA sequence data. Molecular Phylogenetics and Evolution. 66. 215 - 222 [IF20134,018]
  • Bowers E. , Muclinger P. , Bureš S. , Kučerová L. , Nádvorník P. , Krist M. : (2013) Cross-fostering eggs reveals that female collared flycatchers adjust clutch sex ratios according to parental ability to invest in offspring. Molecular Ecology. 22. 215 - 228 [IF20135,840]
  • Foissac X. , Danet J. , Malembic-Maher S. , Salar P. , Šafářová D. , Válová P. , Navrátil M. : (2013) Tuf and secY PCR amplification and genotyping of phytoplasmas. Methods in Molecular Biology. 938. 189 - 204 [IF]
  • Kubienová L. , Kopečný D. , Tylichová M. , Briozzo P. , Skopalová J. , Šebela M. , Navrátil M. , Tache R. , Luhová L. , Barroso J. , Petřivalský M. : (2013) Structural and functional characterization of a plant S-nitrosoglutathione reductase from Solanum lycopersicum. Biochimie. 95. 889 - 902 [IF20133,123]
  • Kast R. , Boockvar J. , Bruning A. , Cappello F. , Chang W. , Cvek B. , Dou Q. , Duenas-Gonzalez A. , Efferth T. , Focosi D. , Ghaffari S. , Karpel-Masler G. , Ketola K. , Khoshnevisan A. , Keizman D. , Magne T. , Marosi C. , McDonald K. , Munoz M. , Paranipe A. , Pourgholami M. , Sardi I. , Sella A. , Srivenugopal K. , Tuccori M. , Wang W. , Wirtz C. , Halatsch M. : (2013) A conceptually new treatment approach for relapsed glioblastoma: Coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care. Oncotarget. 4. 502 - 530 [IF20136,627]
  • Cvek B. : (2013) IXAZOMIB CITRATE Proteasome Inhibitor Oncolytic . Drugs of the Future. 37. 561 - 565 [IF20130,253]
  • Belic A. , Toth K. , Vrzal R. , Temesvari M. , Porrogi P. , Orban E. , Rozman D. , Dvořák Z. , Monostory K. : (2013) Dehydroepiandrosterone post-transcriptionally modifies CYP1A2 induction involving androgen receptor. Chemico-Biological Interactions. 203. 597 - 603 [IF20132,982]
  • Kameníčková A. , Anzenbacherová E. , Pávek P. , Soshilov A. , Denison M. , Zapletalová M. , Anzenbacher P. , Dvořák Z. : (2013) Effects of anthocyanins on the AhR-CYP1A1 signaling pathway in human hepatocytes and human cancer cell lines. Toxicology Letters. 221. 1 - 8 [IF20133,355]
  • Vrzalová (Dořičáková) A. , Vrzal R. , Dvořák Z. : (2013) A non-radioactive electrophoretic mobility shift assay for measurement of pregnane X receptor binding activity to CYP3A4 response element. Electrophoresis. 34. 1863 - 1868 [IF20133,161]
  • James D. , Varga A. , Jesperson G. , Navrátil M. , Šafářová D. , Constable F. , Horner M. , Eastwell K. , Jelkmann W. : (2013) Identification and complete genome analysis of a virus variant or putative new foveavirus associated with apple green crinkle disease. Archives of Virology. 158. 1877 - 1887 [IF20132,282]
  • Navrátilová L. , Šafářová D. , Raclavský V. : (2013) Usefulness of PCR-HRMA in identification of non-fermentative Gram-negative rods recovered from patients suffering from cystic fibrosis or chronic obstructive pulmonary disease. Folia Microbiologica. 59. 17 - 21 [IF20131,145]
  • Starý M. , Válová P. , Šafářová D. , Lauterer P. , Ackermann P. , Navrátil M. : (2013) Survey and molecular detection of Bois noir in vineyards of the Czech Republic - Short communication. Horticultural Science. 40. 83 - 87 [IF20130,920]
  • Šafářová D. , Navrátil M. , Paprštein F. , Candresse T. , Marais A. : (2013) Cherry virus A infecting cherries and plums in the Czech Republic - Short communication. Horticultural Science. 40. 37 - 39 [IF20130,920]
  • Kubienová L. , Kopečný D. , Tylichová M. , Briozzo P. , Skopalová J. , Šebela M. , Navrátil M. , Tache R. , Luhová L. , Barroso J. , Petřivalský M. : (2013) Structural and functional characterization of a plant S-nitrosoglutathione reductase from Solanum lycopersicum. Biochimie. 95. 889 - 902 [IF20133,123]
  • Vrzal R. , Frauenstein K. , Proksch P. , Abel J. , Dvořák Z. , Haarmann-Stemmann T. : (2013) Khellin and Visnagin Differentially Modulate AHR Signaling and Downstream CYP1A Activity in Human Liver Cells. PLoS One. 8. 74917 - 74917 [IF20133,534]
  • Vrzal R. , Knoppová B. , Bachleda P. , Dvořák Z. : (2013) Effects of Oral Anorexiant Sibutramine on the Expression of Cytochromes P450s in Human Hepatocytes and Cancer Cell Lines. Journal of Biochemical and Molecular Toxicology. 27. 515 - 521 [IF20131,317]
  • Kameníčková A. , Pečová M. , Bachleda P. , Dvořák Z. : (2013) Effects of artificial sweeteners on the AhR- and GR-dependent CYP1A1 expression in primary human hepatocytes and human cancer cells. Toxicology in Vitro. 27. 2283 - 2288 [IF20133,207]
  • Stejskalová L. , Rulcová A. , Vrzal R. , Dvořák Z. , Pávek P. : (2013) Dexamethasone accelerates degradation of aryl hydrocarbon receptor (AHR) and suppresses CYP1A1 induction in placental JEG-3 cell line. Toxicology Letters. 223. 183 - 191 [IF20133,355]
  • Dvořák Z. , Grycová (Novotná) A. , Vančo J. , Trávníček Z. : (2013) Influence of gold(I) complexes involving adenine derivatives on major drug-drug interaction pathway. Toxicology in Vitro. 27. 2331 - 2334 [IF20133,207]
  • Rulcová A. , Krausová L. , Smutný T. , Vrzal R. , Dvořák Z. , Jover R. , Pávek P. : (2013) Glucocorticoid receptor regulates organic cation transporter 1 ( OCT1, SLC22A1) expression via HNF4α up-regulation in primary human hepatocytes. Pharmacological Reports. 65. 1322 - 1335 [IF20132,165]
  • Kubienová L. , Sedlářová M. , Wünschová A. , Piterková J. , Luhová L. , Mieslerová B. , Lebeda A. , Navrátil M. , Petřivalský M. : (2013) Effect of Extreme Temperatures on Powdery Mildew Development and Hsp70 Induction in Tomato and Wild Solanum spp. Plant Protection Science. 49. 41 - 54 [IF]

2012

  • Dvořák Z. , Štarha P. , Šindelář Z. , Trávníček Z. : (2012) Evaluation of in vitro cytotoxicity of one-dimensional chain [Fe(salen)(L)](n) complexes against human cancer cell lines. Toxicology In Vitro. 23. 480 - 484 [IF20122,650]
  • Kameníčková A. , Vrzal R. , Dvořák Z. : (2012) Effects of ready to drink teas on AhR- and PXR-mediated expression of cytochromes P450 CYP1A1 and CYP3A4 in human cancer cell lines and primary human hepatocytes. Food Chemistry. 4. 1201 - 1206 [IF20123,334]
  • Kameníčková A. , Dvořák Z. : (2012) Effects of flavored mineral waters on AhR-CYP1A1 signaling pathway in primary human hepatocytes and in human hepatic and intestinal cancer cells. Food and Chemical Toxicology. 50. 1933 - 1939 [IF20123,010]
  • Vrzal R. , Dvořák Z. : (2012) A paradigm for AhR-mediated alleviation of type 1 diabetes mellitus pathology by isoquinoline alkaloid berberine. Food Chemistry. 133. 1671 - 1672 [IF20123,334]
  • Cvek B. : (2012) Nonprofit drugs as the salvation of the world's healthcare systems: the case of Antabuse (disulfiram). Drug Discovery Today. 17. 409 - 412 [IF20126,551]
  • Šafářová D. , Navrátil M. , Faure C. , Candresse T. , Marais A. : (2012) First Report of Apricot pseudo-chlorotic leaf spot virus Infecting Plum (Prunus domestica) in the Czech Republic. Plant Disease. 96. 461 - 461 [IF20122,455]
  • Grycová (Novotná) A. , Pávek P. , Dvořák Z. : (2012) Construction and characterization of a reporter gene cell line for assessment of human glucocorticoid receptor activation. European Journal of Pharmaceutical Sciences. 47. 842 - 847 [IF20122,987]
  • Trávníček Z. , Vančo J. , Hošek J. , Buchtík R. , Dvořák Z. : (2012) Cellular responses induced by Cu(II) quinolinonato complexes in human tumor and hepatic cells. Chemistry Central Journal. 6. [IF20121,312]
  • Škrott Z. , Cvek B. : (2012) Diethyldithiocarbamate complex with copper: the mechanism of action in cancer cells. Mini-Reviews in Medicinal Chemistry. 12. 1184 - 1192 [IF20122.865]

2011

  • Brtko J. , Dvořák Z. : (2011) Role of Retinoids, Rexinoids and Thyroid Hormone in the Expression of Cytochrome P450 Enzymes. Current Drug Metabolism. 12. 71 - 88 [IF20115,113]
  • Buchtík R. , Trávníček Z. , Vančo J. , Herchel R. , Dvořák Z. : (2011) Synthesis, characterization, DNA interaction and cleavage, and in vitro cytotoxicity of copper(II) mixed-ligand complexes with 2-phenyl-3-hydroxy-4(1H)-quinolinone. Dalton Transactions. 40. 9404 - 9412 [IF20113,838]
  • Candresse T. , Saenz P. , Garcia J. , Boscia D. , Navrátil M. , Gorris M. : (2011) Analysis of the Epitope Structure of Plum pox virus Coat Protein. Phytopathology. 101. 611 - 619 [IF20112,799]
  • Cvek B. : (2011) Targeting Malignancies with Disulfiram (Antabuse): Multidrug Resistance, Angiogenesis, and Proteasome. Current Cancer Drug Targets. 11. 332 - 337 [IF20114,327]
  • Cvek B. , Dvořák Z. : (2011) The Ubiquitin-Proteasome System (UPS) and the Mechanism of Action of Bortezomib. Current Pharmaceutical Design. 17. 1483 - 1499 [IF20113,870]
  • Cvek B. : (2011) Antabuse repurposing: we need more knowledge and wide international support. International Journal of Cancer. 129. 1286 - 1287 [IF20115,444]
  • Dvořák Z. , Vrzal R. : (2011) Berberine reduces insulin resistance: the roles for glucocorticoid receptor and aryl hydrocarbon receptor. Fertility ans Sterility. 95. 7 - 7 [IF20113,564]
  • Dvořák Z. , Štarha P. , Trávníček Z. : (2011) Evaluation of in vitro cytotoxicity of 6-benzylaminopurine carboplatin derivatives against human cancer cell lines and primary human hepatocytes. Toxicology in Vitro. 25. 652 - 656 [IF20112,775]
  • Dvořák Z. : (2011) Drug-drug interactions by azole antifungals: Beyond a dogma of CYP3A4 enzyme activity inhibition. Toxicology Letters. 202. 129 - 132 [IF20113,230]
  • Kameníčková A. , Vrzal R. , Dvořák Z. : (2011) Effects of ready to drink teas on AhR- and PXR-mediated expression of cytochromes P450 CYP1A1 and CYP3A4 in human cancer cell lines and primary human hepatocytes. Food Chemistry. 131. 1201 - 1206 [IF20113,855]
  • Kohalmy K. , Vrzal R. : (2011) Regulation of Phase II Biotransformation Enzymes by Steroid Hormones. Current Drug Metabolism. 12. 104 - 123 [IF20115,113]
  • Krausová L. , Stejskalová L. , Wang H. , Vrzal R. , Dvořák Z. , Mani S. , Pávek P. : (2011) Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene. Biochemical Pharmacology. 82. 1771 - 1780 [IF20114,705]
  • Kyseláková H. , Prokopová J. , Nauš J. , Novák O. , Navrátil M. , Šafářová D. , Špundová M. , Ilík P. : (2011) Photosynthetic alterations of pea leaves infected systemically by pea enation mosaic virus: A coordinated decrease in efficiencies of CO2 assimilation and photosystem II photochemistry. Plant Physiology and Biochemistry. 49. 1279 - 1289 [IF20112,838]
  • Monostory K. , Dvořák Z. : (2011) Steroid Regulation of Drug-Metabolizing Cytochromes P450. Current Drug Metabolism. 12. 154 - 172 [IF20115,133]
  • Grycová (Novotná) A. , Pávek P. , Dvořák Z. : (2011) Novel Stably Transfected Gene Reporter Human Hepatoma Cell Line for Assessment of Aryl Hydrocarbon Receptor Transcriptional Activity: Construction and Characterization. Environmental Science & Technology. 45. 10133 - 10139 [IF20115,228]
  • Panáček A. , Prucek R. , Šafářová D. , Dittrich M. , Richtrová J. , Beničková K. , Zbořil R. , Kvítek L. : (2011) Acute and Chronic Toxicity Effects of Silver Nanoparticles (NPs) on Drosophila melanogaster.. Environmental Science & Technology. 45. 4974 - 4979 [IF20115,228]
  • Rohozková J. , Navrátil M. : (2011) P1 peptidase - a mysterious protein of family Potyviridae. Journal of Biosciences. 36. 189 - 200 [IF20111.648]
  • Šafářová D. , Lauterer P. , Korbasová Z. , Starý M. , Válová P. , Navrátil M. : (2011) Hyalesthes obsoletus, a vector of stolbur phytoplasma: current situation in South Moravia, Czech Republic. Bulletin of Insectology. 64. 127 - 128 [IF20110,592]
  • Šafářová D. , Válová P. , Flídr P. , Navrátil M. : (2011) Molecular identification of 16SrIII and 16SrXII phytoplasma groups in Chenopodium album in Czech Republic. Bulletin of Insectology. 64. 85 - 86 [IF20110,592]
  • Stejskalová L. , Dvořák Z. , Pávek P. : (2011) Endogenous and Exogenous Ligands of Aryl Hydrocarbon Receptor: Current State of Art. Current Drug Metabolism. 12. 198 - 2012 [IF20115,113]
  • Stejskalová L. , Večeřová L. , Perez L. , Vrzal R. , Dvořák Z. , Nachtigal P. , Pávek P. : (2011) Aryl Hydrocarbon Receptor and Aryl Hydrocarbon Nuclear Translocator Expression in Human and Rat Placentas and Transcription Activity in Human Trophoblast Cultures. Toxicological Sciences. 123. 26 - 36 [IF20114,652]
  • Vrzal R. , Dořičáková A. , Grycová (Novotná) A. , Bachleda P. , Bitman M. , Pávek P. , Dvořák Z. : (2011) Valproic acid augments vitamin D receptor-mediated induction of CYP24 by vitamin D3: A possible cause of valproic acid-induced osteomalacia?. Toxicology Letters. 200. 146 - 153 [IF20113,230]
  • Wlcek K. , Svoboda M. , Riha J. , Zakaria S. , Olszewski U. , Dvořák Z. , Sellner F. , Ellinger I. , Jäger W. , Thalhammer T. : (2011) The analysis of organic anion transporting polypeptide (OATP) mRNA and protein patterns in primary and metastatic liver cancer. Cancer Biology & Therapy. 9. 801 - 811 [IF20112,638]

2010

  • Bachleda P. , Vrzal R. , Dvořák Z. : (2010) Resveratrol Enhances NK Cell Cytotoxicity: Possible Role for Aryl Hydrocarbon Receptor. Journal of Cellular Physiology. 225. 289 - 290 [IF20103,986]
  • Cvek B. : (2010) Antabuse (disulfiram) as a pilot case of nonprofit drug. International Journal of Cancer. 127. 2486 - 2486 [IF20104,926]
  • Dvořák Z. , Pávek P. : (2010) Regulation of drug-metabolizing cytochrome P450 enzymes by glucocorticoids. Drug Metabolism Reviews. 42. 621 - 635 [IF20106,283]
  • Dvořák Z. : (2010) Berberine: A multipotent remedy with unknown cellular target?. Poultry Science. 89. 1787 - 1787 [IF20101,582]
  • Dvořák Z. , Vrzal R. , Štarha P. , Klanicová A. , Trávníček Z. : (2010) Effects of dinuclear copper(II) complexes with 6-(benzylamino)purine derivatives on AhR and PXR dependent expression of cytochromes P450 CYP1A2 and CYP3A4 genes in primary cultures of human hepatocytes. Toxicology in Vitro. 24. 425 - 429 [IF20102,546]
  • Grycová (Novotná) A. , Dořičáková A. , Vrzal R. , Maurel P. , Pávek P. , Dvořák Z. : (2010) Investigation of Orlistat effects on PXR activation and CYP3A4 expression in primary human hepatocytes and human intestinal LS174T cells. European Journal of Pharmaceutical Sciences. 41. 276 - 280 [IF20103,291]
  • Pávek P. , Pospěchová K. , Švecová L. , Syrová Z. , Stejskalová L. , Blažková J. , Dvořák Z. , Blahoš J. : (2010) Intestinal cell-specific vitamin D receptor (VDR)-mediated transcriptional regulation of CYP3A4 gene. Biochemical Pharmacology. 79. 277 - 287 [IF20104,889]
  • Rulcová A. , Prokopová I. , Krausová L. , Bitman M. , Vrzal R. , Dvořák Z. , Blahoš J. , Pávek P. : (2010) Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug-metabolizing cytochrome P450 enzymes. Journal of Thrombosis and Haemostasis. 8. 2708 - 2717 [IF20105,439]
  • Smýkal P. , Šafářová D. , Navrátil M. : (2010) Marker assisted pea breeding: eIF4E allele specific markers to pea seed-borne mosaic virus (PSbMV) resistance. Molecular Breeding. 26. 425 - 438 [IF20102,193]
  • Trávníček Z. , Štarha P. , Popa I. , Vrzal R. , Dvořák Z. : (2010) Roscovitine-based CDK inhibitors acting as N-donor ligands in the platinum(II) oxalato complexes: Preparation, characterization and in vitro cytotoxicity. European Journal of Medicinal Chemistry. 45. 4609 - 4614 [IF20103,193]
  • Vrzal R. , Gerbal-Chaloin S. , Maurel P. , Dvořák Z. : (2010) Comparative Effects of Microtubules Disruption on Glucocorticoid Receptor Functions in Proliferating and Quiescent Cells. International Journal of Toxicology. 29. 326 - 335 [IF20101,762]
  • Vrzal R. , Štarha P. , Dvořák Z. , Trávníček Z. : (2010) Evaluation of in vitro cytotoxicity and hepatotoxicity of platinum(II) and palladium(II) oxalato complexes with adenine derivatives as carrier ligands. Journal of Inorganic Biochemistry. 104. 1130 - 1132 [IF20103,317]
  • Vrzal R. , Kubešová K. , Pávek P. , Dvořák Z. : (2010) Benzodiazepines medazepam and midazolam are activators of pregnane X receptor and weak inducers of CYP3A4: Investigation in primary cultures of human hepatocytes and hepatocarcinoma cell lines. Toxicology Letters. 193. 183 - 188 [IF20103,581]

2009

  • Bachleda P. , Vrzal R. , Dvořák Z. : (2009) Activation of MAPKs influences the expression of drug-metabolizing enzymes in primary human hepatocytes. General Physiology and Biophysics. 28. 316 - 320 [IF20090,741]
  • Bachleda P. , Vrzal R. , Pivnička J. , Cvek B. , Dvořák Z. : (2009) Examination of Zolpidem effects on AhR- and PXR-dependent expression of drug-metabolizing cytochromes P450 in primary cultures of human hepatocytes. Toxicology Letters. 191. 74 - 78 [IF20093,479]
  • Bergougnoux V. , et al. ,. : (2009) The 7B-1 mutation in tomato (Solanum lycopersicum L.) confers a blue light-specific lower sensitivity to coronatine, a toxin produced by Pseudomonas syringae pv. tomato. Journal of Experimental Botany. 60. 1219 - 1230 [IF20094.271]
  • Cvek B. : (2009) Failure of Ditiocarb (Diethyldithiocarbamate) Therapy: Was Diet the Reason?. Current HIV Research. 7. 254 - 254 [IF20091,978]
  • Cvek B. : (2009) Combating endometriosis by blocking proteasome and nuclear factor-kappa B pathways. Human Reproduction. 24. 2967 - 2967 [IF20093,859]
  • Fialová R. , Válová P. , Balakishiyeva G. , Danet J. , Šafářová D. , Foissac X. , Navrátil M. : (2009) GENETIC VARIABILITY OF STOLBUR PHYTOPLASMA IN ANNUAL CROP AND WILD PLANT SPECIES IN SOUTH MORAVIA. Journal of Plant Pathology. 91. 411 - 416 [IF20090.974]
  • Fránová J. , Navrátil M. , Jakešová H. : (2009) Molecular Identification of Stolbur Phytoplasma Associated with Red Clover Dwarf Disease Symptoms. Journal of Phytopathology. 157. 502 - 506 [IF20090,983]
  • Gadiou S. , Šafářová D. , Navrátil M. : (2009) DIFFERENTIATION OF PLUM POX VIRUS ISOLATES BY SINGLE-STRAND CONFORMATION POLYMORPHISM AND LOW-STRINGENCY SINGLE SPECIFIC PRIMER PCR ANALYSIS OF HC-Pro GENOME REGION. Acta Virologica. 53. 53 - 56 [IF20090,746]
  • Kocábek T. , et al. ,. : (2009) Boron-regulated hypocotyl elongation is affected in Arabidopsis mutants with defects in light signalling pathways. Environmental and Experimental Botany. 67. 101 - 111 [IF20093.164]
  • Monostory K. , Pascussi J. , Kóbori L. , Dvořák Z. : (2009) Hormonal regulation of CYP1A expression. Drug Metabolism Reviews. 41. 547 - 572 [IF20095,430]
  • Navrátil M. , Válová P. , Fialová R. , Lauterer P. , Šafářová D. , Starý M. : (2009) The incidence of stolbur disease and associated yield losses in vegetable crops in South Moravia (Czech Republic). Crop Protection. 28. 898 - 904 [IF20091,331]
  • Navrátil M. , Šafářová D. , Válová P. , Fránová J. , Šimková M. : (2009) Phytoplasma Associated with Witches'-Broom Disease of Ulmus minor MILL. in the Czech Republic: Electron Microscopy and Molecular Characterization. Folia Microbiologica. 54. 37 - 42 [IF20090,978]
  • Ondřej V. , Kitner M. , Doležalová I. , Nádvorník P. , Navrátilová B. , Lebeda A. : (2009) Chromatin structural rearrangement during dedifferentiation of protoplasts of Cucumis sativus L. Molecules and Cells. 27. 443 - 447 [IF20091,878]
  • Pospěchová K. , Rozehnal V. , Stejskalová L. , Vrzal R. , Pospíšilová N. , Jamborová G. , May K. , Siegmund W. , Dvořák Z. , Nachtigal P. , Semecký V. , Pávek P. : (2009) Expression and activity of vitamin D receptor in the human placenta and in choriocarcinoma BeWo and JEG-3 cell lines. Molecular and Cellular Endocrinology. 299. 178 - 187 [IF20093,503]
  • Vrzal R. , Stejskalová L. , Monostory K. , Maurel P. , Bachleda P. , Pávek P. , Dvořák Z. : (2009) Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes. Chemico-Biological Interactions. 179. 288 - 296 [IF20092,457]

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