The Department of Inorganic Chemistry guarantees the studies in the fields of Inorganic Chemistry, Bioinorganic Chemistry, and Chemistry for Teaching in bachelor's, master's and doctoral study programmes.
As a part of our research, we focus on the preparation and study of new coordination compounds of transition metals, in particular, on the development of new compounds with medicinal application potential (e.g. substances with antitumour, anti-inflammatory or antidiabetic activity or contrast agents for diagnostic imaging methods) or compounds with interesting magnetic, optical or catalytic properties with industrial application potential (e.g. high-density storage media, various types of sensors).
Our teaching activites, as a guarantor of Chemistry for Teaching studies at the Faculty of Science of Palacký University, are also focused on increasing pupils' and students' interest in science and motivation to study science, co-organizing chemical Olympics and also on extracurricular chemical activities for primary and secondary school students.
News
Publication in Inorganic Chemistry Frontiers
29. January 2025
Publication entitled "Anticancer iridium(III) cyclopentadienyl complexes" (author: P. Štarha) has been published in the chemistry journal Inorganic Chemistry Frontiers.
This review provides the reader with an overview of the anticancer active Ir(III) cyclopentadienyl coordination compounds and the diverse chemical, biochemical and biological methods used in their research and development. Structure-activity relationships (SAR) and mechanisms of action (MoA) are discussed with respect to anticancer activity and in comparison to their structural Ru(II), Rh(III) and Os(II) analogues. Considerable attention is paid to the discussion of in vivo anticancer activity and related aspects such as drug delivery strategies, multicomponent compounds or photodynamic therapy.
