Mgr. Miroslav PEŘINA, Ph.D.
Telephone:
585634914
Workplace:
Katedra experimentální biologie
Org. unit:
Přírodovědecká fakulta
Address:
Šlechtitelů 27 A (hlavní budova)
Room number:
3.22
Profession:
Ph.D. student/vědecký pracovník
Selected publications
Peřina M., Kiss MA., Mótyán G., Szczyrbová E., Eliáš M., Študent V., Kurfürstová D., Kovalová M., Mada L., Bouchal J., Jorda R.
A-ring-fused pyrazoles of dihydrotestosterone targeting prostate cancer cells via the downregulation of the androgen receptor.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.
2023.
(ČLÁNEK)
ČLÁNEK
Moradi M., Mousavi A., Řezníčková E., Peřina M., Vojáčková V., Jorda R., Grúz J., Kryštof V., Foroumadi A.
Identification of furo[2,3-d]pyrimidin-4-ylsulfanyl-1,3,4-thiadiazole derivatives as novel FLT3-ITD inhibitors.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.
2024.
Peřina M., Börzsei R., Ágoston H., Vojáčková V., Jorda R.
Synthesis and estrogenic activity of BODIPY-labeled estradiol conjugates.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES.
2024.
Van Goubergen J., Peřina M., Handle F.
Targeting the CLK2/SRSF9 splicing axis in prostate cancer leads to decreased ARV7 expression.
Molecular Oncology.
2024.
Kiss MA., Peřina M., Bereczki L., Bělíček J., Jorda R.
Dihydrotestosterone-based A-ring-fused pyridines: Microwave-assisted synthesis and biological evaluation in prostate cancer cells compared to structurally related quinolines.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY.
2023.
Kovalová M., Havlíček L., Djukic S., Peřina M., Pospíšil T., Řezníčková E., Jorda R., Kryštof V.
Characterization of new highly selective pyrazolo[4,3-d]pyrimidine inhibitor of CDK7.
BIOMEDICINE & PHARMACOTHERAPY.
2023.
Gonzalez G., Kvasnica M., Svrčková K., Peřina M., Jorda R.
Ring-fused 3β-acetoxyandrost-5-enes as novel neuroprotective agents with cholinesterase inhibitory properties.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY.
2023.
Vlková K., Padrtová R., Gucký T., Peřina M., Řezníčková E., Kryštof V.
Synthesis and biological activity evaluation of novel 3,5,7-trisubstituted pyrazolo[1,5-a]pyrimidines.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS.
2023.
Peřina M., Kiss A., Mernyák E., Mada L., Jorda R.
Synthesis of hydrocortisone esters targeting androgen and glucocorticoid receptors in prostate cancer in vitro.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY.
2023.
Řezníčková E., Krajčovičová S., Peřina M., Kovalová M., Soural M., Kryštof V.
Modulation of FLT3-ITD and CDK9 in acute myeloid leukaemia cells by novel proteolysis targeting chimera (PROTAC).
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.
2022.
Vlková K., Gucký T., Peřina M., Řezníčková E., Kryštof V.
Synthesis and biological activity evaluation of novel 2,6,9-trisubstituted purine conjugates as potential protein kinases inhibitors.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS.
2022.
Rudovich AS., Peřina M., Krech AV., Kvasnica M., Mada L., Jorda R.
Synthesis and Biological Evaluation of New Isoxazolyl Steroids as Anti-Prostate Cancer Agents.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
2022.
Tomanová M., Kozlanská K., Jorda R., Jedinák L., Havlíková T., Řezníčková E., Peřina M., Klener P., Dolníková A., Cankař P., Kryštof V.
Synthesis and Structural Optimization of 2,7,9-Trisubstituted purin-8-ones as FLT3-ITD Inhibitors.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
2022.
Jorda R., Havlíček L., Peřina M., Vojáčková V., Pospíšil T., Grúz J., Strnad M., Kryštof V.
3,5,7-Substituted Pyrazolo[4,3-d]Pyrimidine Inhibitors of Cyclin-Dependent Kinases and Cyclin K Degraders.
JOURNAL OF MEDICINAL CHEMISTRY.
2022.
Jansa J., Jorda R., Škerlová J., Peřina M., Řezníčková E., Heger T., Gucký T., Kryštof V.
Imidazo[1,2-c]pyrimidin-5(6H)-one inhibitors of CDK2: Synthesis, kinase inhibition and co-crystal structure.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.
2021.
Kiss MA., Peřina M., Bazgier V., Jorda R.
Synthesis of dihydrotestosterone derivatives modified in the A-ring with (hetero)arylidene, pyrazolo[1,5-a]pyrimidine and triazolo[1,5-a] pyrimidine moieties and their targeting of the androgen receptor in prostate cancer.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY.
2021.
Dayal N., Řezníčková E., Hernandez DE., Peřina M., Vojáčková V., Kryštof V., Jorda R.
3H-Pyrazolo[4,3-f]quinoline-Based Kinase Inhibitors Inhibit the Proliferation of Acute Myeloid Leukemia Cells In Vivo.
JOURNAL OF MEDICINAL CHEMISTRY.
2021.
Jorda R., Havlíček L., Šturc A., Peřina M., Pospíšil T., Široká J., Urbánek L., Strnad M., Kryštof V.
3,5,7-Substituted Pyrazolo[4,3-d]pyrimidine Inhibitors of Cyclin-Dependent Kinases and Their Evaluation in Lymphoma Models.
JOURNAL OF MEDICINAL CHEMISTRY.
2019.
Uživatel nepovolil zobrazení dat v Portále UP.